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DNA- (2- amino- 3- methylimidazo(4,5- f)quinoline) adduct

Subscribe to New Research on DNA-(2-amino-3-methylimidazo(4,5-f)quinoline) adduct

Also Known As:

2-AMIQ-DNA adduct; IQ-DNA adduct

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 60
- 2-Ring Heterocyclic Compounds
  - Quinolines: 92
    - DNA-(2-amino-3-methylimidazo(4,5-f)quinoline) adduct: 2
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleic Acids: 1996
  - DNA: 103411
    - DNA Adducts: 1199
      - DNA-(2-amino-3-methylimidazo(4,5-f)quinoline) adduct: 2
Genetic Phenomena
- Genetic Processes
  - DNA Damage
    - DNA Adducts: 1199
      - DNA-(2-amino-3-methylimidazo(4,5-f)quinoline) adduct: 2

Related Diseases

1.

Neoplasms (Cancer)

02/01/1994 - "The finding of high cardiac IQ-DNA adduct levels prompted a histopathological study of perfusion-fixed hearts from 10 tumor-bearing monkeys chronically dosed with IQ at 10 mg/kg or 20 mg/kg 5 days per week for 48-80 months. "
05/12/1997 - "It is concluded that (1) the rate of PhIP- and IQ-DNA adduct removal depends on the dose and frequency of administration, (2) urinary PhIP may be a good biomarker of recent PhIP exposure and (3) CLA, I3C and IPO are potential chemopreventive agents against PhIP- or IQ-induced tumors in rodents."

Related Drugs and Biologics

1.	Dihydrotachysterol (AT 10)
2.	2- amino- 1- methyl- 6- phenylimidazo(4,5- b)pyridine