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leupin

a human serpin gene product; shows 91.8% sequence similarity to the squamous cell carcinoma antigen (SCCA); MW 44.8 kDa; amino acid sequence given in first source; GenBank X89015

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Serpins: 906
    - leupin: 1
- Peptides: 82426
  - Serpins: 906
    - leupin: 1
Chemical Actions and Uses
- Pharmacologic Actions: 160
  - Molecular Mechanisms of Pharmacological Action: 24
    - Enzyme Inhibitors: 1659
      - Protease Inhibitors: 6291
        Serine Proteinase Inhibitors: 1371
        Serpins: 906
        leupin: 1

Experts

1.	Barnes, R C: 1 article (07/2000)
2.	Coulter, J: 1 article (07/2000)
3.	Worrall, D M: 1 article (07/2000)

Related Diseases

1.	Uterine Cervical Neoplasms (Cancer of the Cervix) 07/01/2000 - "The confirmation that leupin or SCCA-2 is the more acidic protein and that its expression is significantly elevated in cervical cancer suggests that this gene product may be the more important tumor marker."

Related Drugs and Biologics

1.	Tumor Biomarkers (Tumor Markers)
2.	Proteins (Proteins, Gene)