HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

difuracil

Also Known As:

N-(5-nitrofurfurylidene)-5-nitrofuran-2-(N'-acetyl)carboxamidrazone; PAP 49; PAP-49

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Nitro Compounds: 66
  - Nitrofurans: 69
    - difuracil: 3
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Furans: 85
    - Nitrofurans: 69
      - difuracil: 3

Experts

1.	Chu, Patrick: 1 article (04/2013)
2.	Eapen, Chundamannil E: 1 article (04/2013)
3.	Elias, Elwyn: 1 article (04/2013)
4.	Elias, Joshua E: 1 article (04/2013)
5.	Mackie, Ian: 1 article (04/2013)
6.	Shaw, Jean C: 1 article (04/2013)

Related Diseases

1.	Sepsis (Septicemia) 04/01/1995 - "It was shown in the models of staphylococcal and Coli septicemia of albino mice that by its therapeutic efficacy difuracil (PAP-49) was 1.3 times more active as furazolidone and by 1-2 days earlier eradicated the pathogens in the host." 04/01/1995 - "[Therapeutic effectiveness of furazolidone and difuracil (PAP-49) in experimental staphylococcal and Escherichia septicemia]." 04/01/1995 - "The therapeutic efficacy of a new nitrofuran, N-(5-nitrofurilidene)-5-nitrofuran-2-(N'-acetyl)carboxamidra zone (difuracil or PAP-49) in experimental staphylococcal and Coli septicemia was stated and compared to that of furazolidone. "
2.	Portal Hypertension 04/01/2013 - "A patient with non-cirrhotic intrahepatic portal hypertension (NCIPH), ulcerative colitis and celiac disease developed symptoms of PPH, which had advanced beyond levels which would have made her an eligible candidate for liver transplantation (mean pulmonary artery pressure (PAP) 49 mm Hg). "
3.	Ulcerative Colitis 04/01/2013 - "A patient with non-cirrhotic intrahepatic portal hypertension (NCIPH), ulcerative colitis and celiac disease developed symptoms of PPH, which had advanced beyond levels which would have made her an eligible candidate for liver transplantation (mean pulmonary artery pressure (PAP) 49 mm Hg). "
4.	Celiac Disease (Celiac Sprue) 04/01/2013 - "A patient with non-cirrhotic intrahepatic portal hypertension (NCIPH), ulcerative colitis and celiac disease developed symptoms of PPH, which had advanced beyond levels which would have made her an eligible candidate for liver transplantation (mean pulmonary artery pressure (PAP) 49 mm Hg). "
5.	Body Weight (Weight, Body) 01/01/1997 - "It was shown that the minimum inhibitory concentration of both the drugs ranged from 0.01 to 1.56 micrograms/ml. The experiments on rabbits with the use of the drugs in doses of 5 and 10 mg/ kg body weight revealed that unlike furazolidone difuracil induced no noticable qualitative or quantitative changes in the intestinal microflora composition."

Related Drugs and Biologics

1.	difuracil
2.	Furazolidone (Furoxone)

Related Therapies and Procedures

1.	Liver Transplantation