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dehydroilludin M
RN given for (R)-isomer; structure in first source
Networked:
1
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Terpenes: 1461
Sesquiterpenes: 1370
dehydroilludin M: 1
Related Diseases
1.
Carcinoma (Carcinomatosis)
05/01/1995 - "
Dehydroilludin M retained the in vitro relative selective cytotoxicity for carcinomas and myeloid leukemia cell lines noted with the parent illudin compounds.
"
05/01/1995 - "
The efficacy of dehydroilludin M in the MV522 lung carcinoma model exceeded that of 9 known anticancer drugs, and equaled that of mitomycin C.
"
2.
Neoplasms (Cancer)
05/01/1995 - "
One analog, dehydroilludin M, inhibited xenograft growth and prolonged life span of tumor bearing animals, when administered IP or IV, whereas the parent Illudin S compound was ineffective.
"
3.
Myeloid Leukemia (Leukemia, Myelocytic)
05/01/1995 - "
Dehydroilludin M retained the in vitro relative selective cytotoxicity for carcinomas and myeloid leukemia cell lines noted with the parent illudin compounds.
"
Related Drugs and Biologics
1.
Mitomycin (Mitomycin-C)
2.
illudin S