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4-hydroxynethyl-furoxan-3-carboxamide

structure given in first source

Also Known As:

CAS 1609; CAS-1609

Networked: 2 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Oxazoles: 89
      - Oxadiazoles: 146
        4-hydroxynethyl-furoxan-3-carboxamide: 2

Related Diseases

1.	Heart Failure 04/01/1995 - "5. In anaesthetized dogs with acute heart failure due to intracoronary injection of microspheres, CAS 1609 (0.3 mg kg-1, i.v.) improved the haemodynamic condition and reduced mortality by 80%. "
2.	Myocardial Ischemia (Ischemic Heart Diseases) 09/01/1995 - "In the present study a novel nitric oxide (NO) donor, CAS-1609, was utilized as a means of coronary NO replenishment in a canine model of myocardial ischemia-reperfusion. "
3.	Necrosis 09/01/1995 - "Moreover, myocardial necrosis as a percentage of the area at risk was reduced from 28.9 +/- 4.3% in the saline group to 8.5 +/- 2.6% in the CAS-1609 group (P < 0.01), while ischemic zone myeloperoxidase activity, indicative of neutrophil infiltration, was also attenuated by 70% with NO therapy. "

Related Drugs and Biologics

1.	Nitric Oxide (Nitrogen Monoxide)
2.	Peroxidase (Myeloperoxidase)

Related Therapies and Procedures

1.	Microspheres (Microsphere)
2.	Therapeutics