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N-tert-butyl-(2-sulfophenyl)nitrone

Neuroprotectant

Also Known As:

2-SPBN; 2-sulfoxy phenyl-N-tert-butylnitrone sodium salt; N-tert-butyl-alpha-(2-sulfophenyl)nitrone; sodium 2-sulfophenyl-N-tert-butyl nitrone

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzenesulfonates
        N-tert-butyl-(2-sulfophenyl)nitrone: 2
- Sulfur Compounds: 278
  - Sulfur Acids
    - Sulfonic Acids: 1605
      - Arylsulfonic Acids
        Arylsulfonates: 1
        Benzenesulfonates
        N-tert-butyl-(2-sulfophenyl)nitrone: 2

Experts

1.	Lennmyr, Fredrik: 1 article (08/2010)
2.	Molnar, Maria: 1 article (08/2010)
3.	Basu, S: 1 article (09/2003)
4.	Liu, X L: 1 article (09/2003)
5.	Nozari, A: 1 article (09/2003)
6.	Rubertsson, S: 1 article (09/2003)
7.	Wiklund, L: 1 article (09/2003)

Related Diseases

1.	Inflammation (Inflammations) 09/01/2003 - "An investigation of the free radical scavenger sodium 2-sulfophenyl-N-tert-butyl nitrone (S-PBN) and the weak vasodilatator Tris buffer mixture (TBM) on cerebral cortical blood flow (CCBF) and the jugular bulb concentration of two eicosanoids, indicators of oxidative stress and inflammation, was undertaken in 30 anaesthetized piglets during cardiopulmonary resuscitation (CPR) and after restoration of spontaneous circulation (ROSC). "
2.	Traumatic Brain Injuries (Traumatic Brain Injury) 08/01/2010 - "Sodium 2-sulfophenyl-N-tert-butyl nitrone (S-PBN) can be administered experimentally and has been shown to be neuroprotective in experimental brain trauma. "

Related Drugs and Biologics

1.	Free Radical Scavengers
2.	Eicosanoids
3.	Tribonate

Related Therapies and Procedures

1.	Cardiopulmonary Resuscitation (CPR)