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integrin alpha8

amino acid sequence in first source; GenBank L36531

Also Known As:

integrin alpha(8)

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Immunologic Receptors: 9
        Integrins: 14304
        Integrin alpha Chains: 91
        integrin alpha8: 5

Experts

1.	Chow, Yu-Hua: 1 article (01/2018)
2.	Hung, Chi F: 1 article (01/2018)
3.	Schnapp, Lynn M: 1 article (01/2018)
4.	Wilson, Carole L: 1 article (01/2018)
5.	Belin, Andrea Carmine: 1 article (01/2016)
6.	Fardell, Camilla: 1 article (01/2016)
7.	Mehdi, Rawand Naiel: 1 article (01/2016)
8.	Nissbrandt, Hans: 1 article (01/2016)
9.	Ran, Caroline: 1 article (01/2016)
10.	Sydow, Olof: 1 article (01/2016)

Related Diseases

1.	Neurodegenerative Diseases (Neurodegenerative Disease) 01/01/2016 - "Integrin alpha 8 (ITGA8) encodes the alpha 8 subunit of the integrin alpha8beta1 protein and has recently been suggested as a new candidate gene for Parkinson's disease, an age related neurodegenerative disease with unknown etiology. "
2.	Parkinson Disease (Parkinson's Disease) 01/01/2016 - "Integrin alpha 8 (ITGA8) encodes the alpha 8 subunit of the integrin alpha8beta1 protein and has recently been suggested as a new candidate gene for Parkinson's disease, an age related neurodegenerative disease with unknown etiology. "
3.	Wilms Tumor (Wilm's Tumor) 01/14/1999 - "Through this work we identified a number of novel target genes for the WT1 transcription factor, including uvomorulin, integrin alpha8 and perlecan, and suggest that WTI may activate the IGF-II gene, also implicated in the development of Wilms' tumor."
4.	Neoplasms (Cancer) 01/01/2009 - "Putative biomarkers such as cell cycle related genes (Cdc37), cancer cell adhesion (Glycam 1, integrin alpha8, integrin alphaX and Clec4n), signal transduction (Tlr2, IL-33, and Ccbp2), migration (Ccr1, Ccl6, and diaphorase 1 (Cyb5r3) and cancer development (epiregulin) can be useful for diagnosis and as prognosis markers and some of the target molecules can be applied for prevention of cancer." 01/01/2009 - "Genes (RAB27b RAS family, IL-1RA, IL-33, chemokine ligand 6, epiregulin, EGF-like domain and cathepsin) related to cancer development (Wnt signaling pathway) and inflammation (chemokine/cytokine signaling pathway, Toll receptor signaling) were up-regulated while genes (troponin, tropomodulin 2, endothelial lipase, FGFR4, integrin alpha8 and adenylate cyclase 8) related to the tumor suppression such as p53 pathway, TGF-beta signaling pathway and cadherin signaling pathway were down-regulated by K-ras oncogene. "
5.	Inflammation (Inflammations) 01/01/2009 - "Genes (RAB27b RAS family, IL-1RA, IL-33, chemokine ligand 6, epiregulin, EGF-like domain and cathepsin) related to cancer development (Wnt signaling pathway) and inflammation (chemokine/cytokine signaling pathway, Toll receptor signaling) were up-regulated while genes (troponin, tropomodulin 2, endothelial lipase, FGFR4, integrin alpha8 and adenylate cyclase 8) related to the tumor suppression such as p53 pathway, TGF-beta signaling pathway and cadherin signaling pathway were down-regulated by K-ras oncogene. "

Related Drugs and Biologics

1.	Cadherins (E-Cadherin)
2.	Epiregulin
3.	Tropomodulin
4.	CD11c Antigen
5.	Chemokines
6.	Transforming Growth Factor beta (TGF-beta)
7.	Cytokines
8.	Biomarkers (Surrogate Marker)
9.	Troponin
10.	Transcription Factors (Transcription Factor)