phosphonium choline

the phosphonium analog of choline where a phosphonium group replaced the natural ammonium group; structure given in first source; RN given refers to the chloride

Also Known As:

Networked: 8 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Hoffmann, Else K: 1 article (03/2003)
2.	Hougaard, Charlotte: 1 article (03/2003)
3.	Lawonn, Peter: 1 article (03/2003)
4.	Wehner, Frank: 1 article (03/2003)

Related Diseases

1.	Neoplasms (Cancer) 11/01/1997 - "Study of the metabolism of choline and phosphatidylcholine in tumors in vivo using phosphonium-choline."
2.	Cataract (Cataracts) 11/01/1989 - "There was a 70% decrease in P-choline in brown cataracts but no significant change from normal in non-brown cataracts. " 11/01/1989 - "The metabolism and concentration of P-choline has been shown to change in animal models of cataract, especially in oxidatively or osmotically stressed rat lenses. " 01/01/1993 - "Phosphorylcholine (P-choline), and phosphorylethanolamine (P-ethanolamine) are among the organic phosphate compounds that decrease in concentration in some cataracts and in lenses that have been subjected to cataractogenic osmotic or oxidative stresses. "
3.	Starvation 04/15/1987 - "Furthermore, the presence of P-choline in plant cells in large excess should be considered as a good marker of membrane utilization after a long period of sucrose starvation and is very likely related to stress."
4.	Glioma (Gliomas) 09/15/1998 - "In glioma cells, permeabilization at high Ca2+ concentration did not affect [14C]choline or [14C]P-choline incorporation into PC. " 09/15/1998 - "C6 rat glioma cells, C3H10T12 fibroblasts and rat hepatocytes were permeabilized with Staphylococcus aureus alpha-toxin, and the incorporation of the radiolabelled precursors choline, phosphocholine (P-choline), ethanolamine and phosphoethanolamine (P-EA) into PC and PE were measured both at high and low Ca2+ concentrations. "
5.	Ascites 03/27/2003 - "In whole-cell recordings on Ehrlich-Lettre-ascites tumour (ELA) cells, the shrinkage-induced activation of a cation conductance with a selectivity ratio P(Na):P(Li):P(K):P(choline):P(NMDG) of 1.00:0.97:0.88:0.03:0.01 was observed. "

Related Drugs and Biologics

1.	Choline (Choline Chloride)
2.	Phosphatidylcholines (Phosphatidylcholine)
3.	Phosphorylcholine (Phosphocholine)
4.	Ethanolamine (Colamine)
5.	phosphorylethanolamine (phosphoethanolamine)
6.	Sucrose (Saccharose)
7.	Phosphotransferases (Kinase)
8.	Phosphates (Orthophosphate)
9.	Cytidine Diphosphate (CDP)
10.	Cations

Related Therapies and Procedures

1.	Lenses