Amyloid beta-Protein Precursor

A single-pass type I membrane protein. It is cleaved by AMYLOID PRECURSOR PROTEIN SECRETASES to produce peptides of varying amino acid lengths. A 39-42 amino acid peptide, AMYLOID BETA-PEPTIDES is a principal component of the extracellular amyloid in SENILE PLAQUES.

Also Known As:

Amyloid Protein Precursor; Amyloid beta Precursor Protein; Protease Nexin 2; Protease Nexin II; Amyloid beta Protein Precursor; Nexin 2, Protease; Nexin II, Protease; beta Amyloid Protein Precursor; beta-Protein Precursor, Amyloid; Amyloid A4 Protein Precursor; beta-Amyloid Protein Precursor

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Amyloid: 36214
    - Amyloidogenic Proteins: 1587
      - Amyloid beta-Protein Precursor: 519
  - Membrane Proteins: 10078
    - Amyloid beta-Protein Precursor: 519
  - Secretory Proteinase Inhibitory Proteins: 234
    - Protease Nexins: 16
      - Amyloid beta-Protein Precursor: 519
  - Protein Precursors: 37
    - Amyloid beta-Protein Precursor: 519

amyloid beta-protein precursor 770 (301-323)

Bio-Agent Context: Research Results