JL 18

a pyridobenzodiazepine derivative bioisoster of clozapine

Also Known As:

8-methyl-6-(4-methyl-1-piperazinyl)-11H-pyrido(2,3-b)(1,4)benzodiazepine; JL-18

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Dyskinesias (Dyskinesia) 07/07/2000 - "Co-administration of JL-18, at low doses (0.1, 0.3 mg/kg) with L-Dopa/benserazide, produced a dose-dependent reduction in L-Dopa-induced dyskinesias without a parallel return to parkinsonism. "
2.	Parkinsonian Disorders (Parkinsonism) 07/07/2000 - "Co-administration of JL-18, at low doses (0.1, 0.3 mg/kg) with L-Dopa/benserazide, produced a dose-dependent reduction in L-Dopa-induced dyskinesias without a parallel return to parkinsonism. "