4- (3- (3- (bis(4- isobutylphenyl)methylamino)benzoyl)- 1H- indol- 1- yl)butyric acid
structure given in first source
Also Known As:
FK 143; FK-143; FK143
Networked: 3
relevant articles (0 outcomes,
1 trials/studies)
Bio-Agent Context: Research Results
Related Diseases
1. | Prostatic Neoplasms (Prostate Cancer)
06/04/1997
- " This study was conducted to determine if a 5alpha-reductase inhibitor, FK143, inhibits the development of prostate cancer in rats. " 06/04/1997
- " The 5alpha-reductase inhibitor FK143 may, at specific doses, reduce the incidence of spontaneously developing prostate cancer; however, whether these findings in rats will apply to humans remains to be determined." 06/04/1997
- " Male ACI/Seg rats, which spontaneously develop prostate cancer, were randomly assigned at 80 weeks of age to receive one of three diets (n = 35/group) containing 0 (i.e., control group), 20, or 200 ppm FK143. "
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2. | Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
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3. | Carcinogenesis
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4. | Atrophy
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