5-methylcytosine-DNA glycosylase

binds equally well to methylated and non-methylated DNA; isolated from developing chicken embryos and mouse fibroblasts; MW 52.5 kDa

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Carcinogenesis 09/05/1996 - "This 5-methylcytosine-DNA glycosylase activity could be involved in carcinogenesis, transcription, replication, differentiation and development through resultant DNA hypomethylation following enzymatic removal of 5-methylcytosine from DNA."
2.	Infections 07/01/2022 - "The genome of the model plant Arabidopsis thaliana encodes four paralogous proteins, two of which, DEMETER (DME) and REPRESSOR OF SILENCING 1 (ROS1), possess 5-methylcytosine-DNA glycosylase activity and are necessary for the regulation of development, response to infections and abiotic stress and silencing of transgenes and mobile elements. "

1.	5-Methylcytosine (5 Methylcytosine)
2.	Proteins (Proteins, Gene)
3.	DNA (Deoxyribonucleic Acid)