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fexofenadine (Allegra)

Subscribe to New Research on fexofenadine

a second generation antihistamine; metabolite of the antihistaminic drug terfenadine; structure in first source; RN refers to HCl

Also Known As:

Allegra; Telfast; Aventis Behring brand of fexofenadine hydrochloride; Aventis Pharma brand of fexofenadine hydrochloride; Aventis brand of fexofenadine hydrochloride; Hoechst brand of fexofenadine hydrochloride; MDL 16,455A; MDL 16.455; MDL 16455; MDL-16455; alpha-(4-(1-carboxy-1-methylethyl)phenyl)-4-hydroxydiphenylmethyl-1-piperidinebutanol; fexofenadine hydrochloride

Networked: 218 relevant articles (54 outcomes, 56 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Meeves, Suzanne: 7 articles (02/2007 - 07/2002)
2.	Kittner, Barbara: 5 articles (07/2008 - 12/2004)
3.	Georges, George: 5 articles (10/2006 - 10/2003)
4.	Bachert, Claus: 4 articles (11/2011 - 04/2003)
5.	Bartra, J: 4 articles (01/2011 - 01/2002)
6.	Lutz, Cheryl: 4 articles (10/2006 - 07/2002)
7.	Berkowitz, Robert B: 4 articles (10/2006 - 07/2002)
8.	Liao, Yuning: 4 articles (10/2006 - 10/2003)
9.	Lipworth, B J: 4 articles (04/2004 - 01/2002)
10.	Miyachi, Yoshiki: 3 articles (01/2015 - 12/2012)

Related Diseases

1.	Seasonal Allergic Rhinitis (Hay Fever) 10/01/1999 - "Once-daily fexofenadine HCl, 120 or 180 mg, significantly improved patient-reported quality of life and reduced performance impairment in work and daily activities due to seasonal allergic rhinitis symptoms compared with placebo." 11/01/1997 - "Fexofenadine HCl is both effective and safe for the treatment of ragweed seasonal allergic rhinitis. " 01/01/2011 - "Systematic review on the efficacy of fexofenadine in seasonal allergic rhinitis: a meta-analysis of randomized, double-blind, placebo-controlled clinical trials." 06/01/2004 - "To evaluate the safety and efficacy of fexofenadine in children with seasonal allergic rhinitis, data were pooled from three, double-blind, randomized, placebo-controlled, parallel-group, 2-week trials in children (6-11 year) with seasonal allergic rhinitis. " 06/01/2004 - "Safety and efficacy of oral fexofenadine in children with seasonal allergic rhinitis--a pooled analysis of three studies."
2.	Urticaria (Hives) 11/01/2012 - "Those with significant improvement of urticaria activity score under fexofenadine at 180 mg were included in the CIU group. " 02/01/1998 - "Fexofenadine 180 or 240mg once daily was significantly more effective than placebo in patients with chronic idiopathic urticaria. " 01/01/2008 - "These studies also support the contention that fexofenadine is effective for the treatment of allergic rhinits and chronic idiopathic urticaria." 04/10/2002 - "Fexofenadine 180 mg is a new antihistamine that is effective in the treatment of chronic urticaria and that has a profile of side effects similar to placebo." 02/01/2000 - "Although no comparative data with other H1 antagonists exist, fexofenadine 180 mg once daily was effective in reducing the symptoms of chronic idiopathic urticaria for up to 6 weeks. "
3.	Rhinitis 12/01/2005 - "Fexofenadine 30 mg bid is effective in reducing the total symptom score of allergic rhinitis including blocked nose and is generally well tolerated. " 10/01/2005 - "Fexofenadine is effective for the treatment of allergic rhinitis. " 12/01/2002 - "Clinical studies have documented the efficacy of fexofenadine in the treatment of allergic rhinitis. " 02/01/2006 - "Efficacy of fexofenadine in the prophylactic control of cat allergen-induced allergic rhinitis." 01/01/2009 - "This study demonstrates that fexofenadine is able to mediate significant changes in different nasal lavage markers from patients with intermittent allergic rhinitis. "
4.	Pruritus (Itching) 02/01/2006 - "Our results suggest that fexofenadine can be beneficial in the daily management of patients with itching due to eczematous disease." 06/01/2005 - "Patients administered fexofenadine (n = 163) experienced significantly greater improvements in MNW and pruritus severity scores compared with the placebo group (n = 92) (P < .001 for both). " 06/01/2003 - "Compared with placebo, fexofenadine significantly improved both diurnal (P = 0.0001) and nocturnal pruritus (P = 0.013). " 06/01/2003 - "Fexofenadine (n = 201) significantly decreased the severity of pruritus compared with placebo (n = 199) (mean change in score -0.75 (unadjusted 95% confidence interval [-0.88, -0.62]) vs. -0.5 [-0.62, -0.38], respectively; P = 0.0005). " 11/01/1999 - "Two subjects developed mild itching, which cleared up after receiving Allegra; the third subject did not respond to the treatment."
5.	Hypersensitivity (Allergy) 03/01/2009 - "FFNS once daily was more effective than fexofenadine and placebo with respect to nighttime sleep disturbance caused by seasonal allergy symptoms." 11/01/2001 - "The present pilot study aimed to evaluate the therapeutic effect exerted by fexofenadine in patients with PAR due to mite allergy. " 05/01/1998 - "Effectiveness and safety of fexofenadine, a new nonsedating H1-receptor antagonist, in the treatment of fall allergies." 12/01/1997 - "Onset of action, efficacy, and safety of a single dose of fexofenadine hydrochloride for ragweed allergy using an environmental exposure unit." 12/01/2009 - "Assessment of the antiobstructive effect of fexofenadine on nasal allergy challenge in patients with seasonal allergic rhinitis."

Related Drugs and Biologics

1.	Cetirizine (Zyrtec)
2.	desloratadine (Aerius)
3.	Pseudoephedrine
4.	olopatadine (Patanol)
5.	Loratadine (Alavert)
6.	levocetirizine
7.	fluticasone (Cutivate)
8.	fexofenadine (Allegra)
9.	Cromolyn Sodium (Cromoglicic Acid)
10.	montelukast (Singulair)

Related Therapies and Procedures

1.	Aftercare (After-Treatment)
2.	Immunotherapy
3.	Phototherapy (Light Therapy)
4.	Oral Administration
5.	Premedication