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methyl 2- (((2- aminoethyl)amino)methyl)- 6- carboxylpyridinehistidinate

structure given in first source

Also Known As:

AMPHIS

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Essential Amino Acids: 1152
    - Histidine: 2980
      - methyl 2-(((2-aminoethyl)amino)methyl)-6-carboxylpyridinehistidinate: 1
  - Cyclic Amino Acids: 3
    - Histidine: 2980
      - methyl 2-(((2-aminoethyl)amino)methyl)-6-carboxylpyridinehistidinate: 1

Experts

1.	Fadok, Valerie A: 1 article (10/2005)
2.	Huynh, Mai-Lan N: 1 article (10/2005)
3.	Kotaru, Chakradhar: 1 article (10/2005)
4.	Malcolm, Kenneth C: 1 article (10/2005)
5.	Tilstra, John A: 1 article (10/2005)
6.	Wenzel, Sally E: 1 article (10/2005)
7.	Westcott, Jay Y: 1 article (10/2005)

Related Diseases

1.

Asthma (Bronchial Asthma)

10/15/2005 - "A decrease in AMphis LPS-responsiveness in severe asthma is manifested by defective apoptotic cell uptake and reduces secretion of inflammatory mediators. "
10/15/2005 - "Human bronchoalveolar lavage macrophages (AMphis) from normal control subjects and subjects with mild-moderate or severe asthma were examined in vitro for phagocytosis of apoptotic human T-cell line Jurkats and secretion of inflammatory mediators. "
10/15/2005 - "In contrast, AMphis from patients with severe asthma had defective LPS-stimulated uptake of apoptotic cells, with associated failure to induce PGE2 and 15-HETE. "
10/15/2005 - "AMphis from normal subjects and patients with mild-moderate asthma were able to phagocytose apoptotic cells in response to LPS, resulting in an induction of the antifibrotic and/or antiinflammatory eicosanoids, prostaglandin E2 (PGE2) and 15-hydroxyeicosatetraenoic acid (HETE). "

Related Drugs and Biologics

1.	Eicosanoids
2.	Dinoprostone (PGE2)
3.	Hydroxyeicosatetraenoic Acids (HETE)
4.	Acids
5.	15-hydroxy-5,8,11,13-eicosatetraenoic acid