methylcitrate synthase

catalyzes the synthesis of (2R,3S)-methylcitric acid; from the yeast Candida lipolitica; more stereospecific than the animal citrate synthase enzyme

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

1.	Brakhage, Axel A: 2 articles (01/2008 - 07/2005)
2.	Brock, Matthias: 2 articles (01/2008 - 07/2005)
3.	Ave, Patrick: 1 article (01/2008)
4.	Dubourdeau, Marc: 1 article (01/2008)
5.	Huerre, Michel: 1 article (01/2008)
6.	Ibrahim-Granet, Oumaïma: 1 article (01/2008)
7.	Latgé, Jean-Paul: 1 article (01/2008)
8.	Gould, Ty A: 1 article (08/2006)
9.	McKinney, John D: 1 article (08/2006)
10.	Muñoz-Elías, Ernesto J: 1 article (08/2006)

1.	Infections 01/01/2008 - "When tested in a murine infection model, the methylcitrate synthase mutant displayed attenuated virulence and, furthermore, was cleared from tissues when mice survived the first phase of acute infection. " 07/01/2005 - "Therefore, an impact of methylcitrate synthase in the infection process is discussed." 07/01/2005 - "In addition, a methylcitrate synthase deletion led to an attenuation of virulence, when tested in an insect infection model and attenuation was even more pronounced, when whitish conidia from glucose/propionate medium were applied. "
2.	Tuberculosis (Tuberculoses) 08/01/2006 - "tuberculosis encodes orthologues of two of the three enzymes of the methylcitrate cycle, methylcitrate synthase and methylcitrate dehydratase, it does not appear to contain a distinct 2-methylisocitrate lyase (MCL). "
3.	Aspergillosis 01/01/2008 - "Methylcitrate synthase from Aspergillus fumigatus is essential for manifestation of invasive aspergillosis."