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1- ((4- fluorobenzoylamino)ethyl)- 4- (7- methoxy- 1- naphthyl)piperazine hydrochloride

a 5-HT(1A) receptor agonist; RN given for HCl salt

Also Known As:

S 14506; S-14506

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Serotonin Syndrome (Syndrome, Serotonin) 01/01/1994 - "Specifically, CDP increased food intake and body weight, whilst S-14506 decreased these measures, possibly due to the induction of the serotonin syndrome. "
2.	Hypothermia 01/01/1994 - "Of particular interest was the observation that S-14506 induced marked hypothermia, to which complete tolerance developed very rapidly (after only 1 day). " 01/01/1994 - "The observation of marked, rapid tolerance to S-14506-induced hypothermia, in conjunction with the absence of withdrawal hyperthermia after prolonged chronic treatment at high doses, suggests that tolerance to this effect of S-14506 can be dissociated from dependence. "
3.	Catalepsy 12/12/1994 - "Raclopride induced catalepsy in rats, whereas like clozapine, S 14506 was virtually ineffective. "
4.	Body Weight (Weight, Body) 01/01/1994 - "Specifically, CDP increased food intake and body weight, whilst S-14506 decreased these measures, possibly due to the induction of the serotonin syndrome. "
5.	Hyperthermia 01/01/1994 - "The observation of marked, rapid tolerance to S-14506-induced hypothermia, in conjunction with the absence of withdrawal hyperthermia after prolonged chronic treatment at high doses, suggests that tolerance to this effect of S-14506 can be dissociated from dependence. "

Related Drugs and Biologics

1.	Raclopride
2.	Cytidine Diphosphate (CDP)
3.	Clozapine (Clozaril)