HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
N- alpha- DTPA- tyrosyl- N- epsilon- DTPA- lysine
Also Known As:
111In-di-DTPA-TL; di-DTPA-TL
Networked:
2
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Peptides: 82426
Oligopeptides: 519
Dipeptides: 945
N-alpha-DTPA-tyrosyl-N-epsilon-DTPA-lysine: 2
Organic Chemicals: 133
Amines: 4871
Polyamines: 3918
Pentetic Acid: 1751
N-alpha-DTPA-tyrosyl-N-epsilon-DTPA-lysine: 2
Carboxylic Acids: 973
Acyclic Acids
Acetates: 4994
Pentetic Acid: 1751
N-alpha-DTPA-tyrosyl-N-epsilon-DTPA-lysine: 2
Related Diseases
1.
Neoplasms (Cancer)
01/01/1999 - "
The time required for the tumor to double in size was respectively 57 and 86 d with 37 and 92.5 MBq F6-734/131I-di-DTPA-TL and 44 and 65 d with 37 and 92.5 MBq 131I-F6.
"
04/01/1995 - "
In patients with colorectal or medullary thyroid cancer, clinical studies performed with an anti-CEA/anti-DTPA-indium bifunctional antibody and an indium-111-labeled di-DTPA-TL bivalent hapten showed that tumor uptake was not modified compared to results for F(ab')2 fragments of the same anti-CEA antibody directly labeled with indium-111, whereas the radioactivity of normal tissues was significantly reduced (3- to 6-fold).
"
2.
medullary Thyroid cancer
04/01/1995 - "
In patients with colorectal or medullary thyroid cancer, clinical studies performed with an anti-CEA/anti-DTPA-indium bifunctional antibody and an indium-111-labeled di-DTPA-TL bivalent hapten showed that tumor uptake was not modified compared to results for F(ab')2 fragments of the same anti-CEA antibody directly labeled with indium-111, whereas the radioactivity of normal tissues was significantly reduced (3- to 6-fold).
"
3.
Weight Loss (Weight Reduction)
01/01/1999 - "
Weight loss was 5%, leukocyte nadirs respectively 1640+/-838 and 1560+/-1160/mm3 and platelet nadirs 1.46+/-0.52 10(6)/mm3 and 0.73+/-0.38 10(6)/mm3 after injections of 37 and 92.5 MBq F6-734/1311-di-DTPA-TL.
"
4.
Melanoma (Melanoma, Malignant)
01/01/1999 - "
Four control groups were treated respectively with (a) 92.5 MBq nonspecific 131I-734 fragments, (b) 92.5 MBq 131I-di-DTPA-TL 48 h after injection of a mixture of irrelevant F6-679 (anti-CEA/anti-histamine) and G7A5-734 (anti-melanoma/anti-DTPA) BsMAb, (c) 250 microg nonradiolabeled F6, and 250 microg F6-734 BsMAb and then 48 h later 1.25 nmol of nonradiolabeled hapten.
"
Related Drugs and Biologics
1.
Haptens
2.
Pentetic Acid (DTPA)
3.
Indium
4.
Indium-111
5.
Histamine (Histamine Dihydrochloride)
Related Therapies and Procedures
1.
Injections