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TCV 295

a potassium channel opener; structure given in first source

Also Known As:

2-(6-bromo-7-chloro-2,2-dimethyl-2H-1,3-benzoxazin-4-yl)pyridine 1-oxide; TCV-295

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198

Related Diseases

1.	Hypertension (High Blood Pressure) 12/01/1994 - "In a 4-week chronic dosing study in SHR, TCV-295 (0.3 mg/kg/day p.o.) produced neither potentiation nor tolerance to its antihypertensive action and no rebound hypertension occurred when drug treatment was discontinued. "
2.	Tachycardia (Tachyarrhythmias) 12/01/1994 - "The antihypertensive effects induced by TCV-295 lasted much longer than those of levcromakalim and nisoldipine, and the reflex tachycardia it evoked was less marked than that evoked by these drugs as compared at doses showing similar maximal hypotensive effects. "

Related Drugs and Biologics

1.	Antihypertensive Agents (Antihypertensives)
2.	Cromakalim (Levcromakalim)
3.	Nisoldipine