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ganciclovir triphosphate

structure given in first source

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purinones: 2
        Hypoxanthines: 1
        Guanine: 1793
        Acyclovir: 4814
        Ganciclovir: 3793
        ganciclovir triphosphate: 5

Experts

1.	Jain, Vaishali: 1 article (01/2021)
2.	Kamble, Vishal: 1 article (01/2021)
3.	Nanda, Adyasha: 1 article (01/2021)
4.	Patel, Himani: 1 article (01/2021)
5.	Warawdekar, Ujjwala M: 1 article (01/2021)
6.	Agbaria, R: 1 article (11/2001)
7.	Blaese, R M: 1 article (11/2001)
8.	Candotti, F: 1 article (11/2001)
9.	Cooney, D A: 1 article (11/2001)
10.	Ford, H: 1 article (11/2001)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2021 - "Pro-drug activation, a modality of cancer therapy leads to Ganciclovir triphosphate (GCV-TP) incorporation into newly synthesized DNA resulting in cell death. " 08/01/2001 - "Introduction of the herpes simplex type I thymidine kinase (HSV-TK) gene into tumor tissue, followed by ganciclovir, initiates a phosphorylation cascade that induces formation of a toxic ganciclovir triphosphate. "
2.	Herpes Simplex 11/30/2001 - "Biosynthetic ganciclovir triphosphate: its isolation and characterization from ganciclovir-treated herpes simplex thymidine kinase-transduced murine cells." 08/01/2001 - "Introduction of the herpes simplex type I thymidine kinase (HSV-TK) gene into tumor tissue, followed by ganciclovir, initiates a phosphorylation cascade that induces formation of a toxic ganciclovir triphosphate. "
3.	Virus Diseases (Viral Diseases) 07/01/1997 - "Intracellular levels of ganciclovir triphosphate and cidofovir diphosphate increased less than two-fold with increasing multiplicity of virus infection. "
4.	Glioblastoma (Glioblastoma Multiforme) 02/01/1999 - "Cytotoxicity and accumulation of ganciclovir triphosphate in bystander cells cocultured with herpes simplex virus type 1 thymidine kinase-expressing human glioblastoma cells."
5.	Colonic Neoplasms (Colon Cancer) 11/30/2001 - "A method is described for the preparation of ganciclovir triphosphate (GCV-TP) using murine colon cancer cells (MC38) transduced with the herpes simplex virus-thymidine kinase (MC38/HSV-tk). "

Related Drugs and Biologics

1.	Thymidine Kinase
2.	Ganciclovir (Cytovene)
3.	Prodrugs
4.	DNA (Deoxyribonucleic Acid)
5.	cidofovir diphosphate

Related Therapies and Procedures

1.	Therapeutics