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ronnel

FENCHLORPHOS was heading 1972-95 (Prov 1972-73); RONNEL was see FENCHLORPHOS 1975-95; use FENCHLORPHOS (NM) to search FENCHLORPHOS 1972-95

Also Known As:

Dermafos; fenchlorfos; fenchlorphos

Networked: 9 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organophosphorus Compounds: 300
  - Organothiophosphorus Compounds
    - ronnel: 9
- Sulfur Compounds: 278
  - Organothiophosphorus Compounds
    - ronnel: 9

Experts

1.	Rimkus, Stacey A: 1 article (01/2018)
2.	Wassarman, David A: 1 article (01/2018)

Related Diseases

1.	Body Weight (Weight, Body) 07/01/1981 - "Actual ronnel intakes averaged 0, 1.01, 2.12 and 4.73 mg/kg body weight daily in trial 2. In trials 3 and 4 , growth and intake were measured in 64 and 32 growing Sprague-Dawley rats, respectively, fed levels of ronnel ranging from 0 to 100 ppm in the diet. " 07/01/1981 - "In trial 1, four groups of eight steers each were given either no ronnel or 4 mg ronnel/kg body weight daily in diets fed at either limited (1.8% of body weight) or ad libitum intake. " 01/01/1983 - "Steers were fed 0, 2, 4 and 8 mg ronnel/kg body weight daily in a Latin square arrangement of treatments with five 28-d periods. " 07/01/1982 - "Rotenone was associated with an increased number of nonpregnant rats and resorptions, at a dose of 10 mg/kg; reductions in maternal body weight gain, fetal weight, and skeletal ossification, together with an increased incidence of extra rib, were found at 5 and 10 mg/kg; but no significant effects were found at 2.5 mg/kg. Increases in the incidence of resorptions in pyrethrum-treated groups and of extra rib in ronnel-treated groups were also observed."
2.	Trichinellosis 01/01/1975 - "[Histochemical study of the effect of phosphoroorganic esters Z-50 (fenchlorfos) and Z-51 (bromophos) on cholinesteras activity in the course of the muscle phase in experimental trichinellosis in mice]."
3.	Schistosomiasis mansoni 01/01/1971 - "[Inefficacy of O, O-dimethyl-O-(2,4,5-trichlorophenyl phosphorothioate) (K-7505 or Ronnel) in the treatment of Schistosomiasis mansoni]." 01/01/1971 - "[Inefficacy of K-7505 (Ronnel) in the treatment of schistosomiasis mansoni]." 10/01/1966 - "Evaluation of Ronnel in schistosomiasis mansoni."
4.	Mitochondrial Diseases (Mitochondrial Disease) 01/01/2018 - "Ronnel and other suppressor compounds are known to cause mitochondrial dysfunction or to inhibit the enzyme acetylcholinesterase, which controls the levels of the neurotransmitter acetylcholine, suggesting that detrimental consequences of reduced ATM kinase activity can be rescued by inhibiting the function of mitochondria or increasing acetylcholine levels. "
5.	Fetal Weight 07/01/1982 - "Rotenone was associated with an increased number of nonpregnant rats and resorptions, at a dose of 10 mg/kg; reductions in maternal body weight gain, fetal weight, and skeletal ossification, together with an increased incidence of extra rib, were found at 5 and 10 mg/kg; but no significant effects were found at 2.5 mg/kg. Increases in the incidence of resorptions in pyrethrum-treated groups and of extra rib in ronnel-treated groups were also observed."

Related Drugs and Biologics

1.	Esters
2.	bromophos (bromofos)
3.	Neurotransmitter Agents (Neurotransmitter)
4.	Rotenone
5.	Phosphotransferases (Kinase)
6.	Enzymes
7.	Acetylcholinesterase
8.	Acetylcholine (Acetylcholine Chloride)