syntrophin alpha1

associated with dystrophin; amino acid sequence has been determined

Also Known As:

SNTA1 protein, human; Snta1 protein, mouse; alpha-syntrophin; alpha1 syntrophin; alpha1-syntrophin, mouse; mouse syntrophin-1; syntrophin, acidic 1, mouse; syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component), human; syntrophin-1; syntrophin-1, mouse

Networked: 12 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843

Experts

1.	Buechler, Christa: 4 articles (01/2020 - 10/2017)
2.	Haberl, Elisabeth M: 4 articles (01/2020 - 10/2017)
3.	Pohl, Rebekka: 4 articles (01/2020 - 10/2017)
4.	Rein-Fischboeck, Lisa: 4 articles (01/2020 - 10/2017)
5.	Adams, Marvin E: 4 articles (08/2010 - 02/2003)
6.	Froehner, Stanley C: 4 articles (08/2010 - 02/2003)
7.	Amiry-Moghaddam, Mahmood: 3 articles (08/2010 - 02/2003)
8.	Bhardwaj, Anish: 3 articles (08/2010 - 02/2003)
9.	Feder, Susanne: 2 articles (01/2020 - 05/2018)
10.	Krautbauer, Sabrina: 2 articles (05/2018 - 01/2018)

Related Diseases

1.	Muscular Dystrophies (Muscular Dystrophy) 03/21/2003 - "These in vivo mouse studies highlight the functional importance of appropriate membrane targeting of nNOS by the dystrophin-associated protein alpha-syntrophin and may have implications for the development of potential gene therapy strategies to treat muscular dystrophy or other muscle-related diseases."
2.	Alcoholic Fatty Liver 01/01/2020 - "Alpha-syntrophin deficiency protects against non-alcoholic steatohepatitis associated increase of macrophages, CD8+ T-cells and galectin-3 in the liver." 10/01/2017 - "The adaptor protein alpha-syntrophin is reduced in human non-alcoholic steatohepatitis but is unchanged in hepatocellular carcinoma." 05/01/2018 - "Alpha-syntrophin null mice are protected from non-alcoholic steatohepatitis in the methionine-choline-deficient diet model but not the atherogenic diet model."
3.	Brain Edema (Cerebral Edema) 02/18/2003 - "The anchoring of AQP4 to alpha-syntrophin may be a target for treatment of brain edema, but therapeutic manipulations of AQP4 must consider the bidirectional water flux through this molecule." 03/01/2004 - "Alpha-syntrophin deletion removes the perivascular but not endothelial pool of aquaporin-4 at the blood-brain barrier and delays the development of brain edema in an experimental model of acute hyponatremia." 02/18/2003 - "Thus alpha-syntrophin-dependent anchoring of AQP4 is sensitive to ischemia, and loss of AQP4 from this site may retard the dissipation of postischemic brain edema. " 03/01/2004 - "A selective removal of perivascular AQP4 by alpha-syntrophin deletion delays the buildup of brain edema (assessed by Diffusion-weighted MRI) following water intoxication, despite the presence of a normal complement of endothelial AQP4. "
4.	Water Intoxication 03/01/2004 - "A selective removal of perivascular AQP4 by alpha-syntrophin deletion delays the buildup of brain edema (assessed by Diffusion-weighted MRI) following water intoxication, despite the presence of a normal complement of endothelial AQP4. "
5.	Obesity 01/01/2018 - "Alpha-syntrophin deficient mice are protected from adipocyte hypertrophy and ectopic triglyceride deposition in obesity."

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Dystrophin
3.	Triglycerides (Triacylglycerol)
4.	Methionine (L-Methionine)
5.	Choline (Choline Chloride)
6.	dystrobrevin
7.	Dystroglycans (Dystroglycan)
8.	Galectin 3 (LGALS3)
9.	Complement System Proteins (Complement)
10.	Bumetanide (Bumex)