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Chlorotoxin

a 4 kDa toxin from Leiurus quinquestriatus; amino acid sequence given in first source; chlorotoxin I-131 (TM601-I131) is Iodine radiolabeled form
Also Known As:
131I-TM-601; TM 601; TM-601; TM601 peptide; chlorotoxin I-131
Networked: 124 relevant articles (4 outcomes, 19 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Zhang, Miqin: 19 articles (01/2019 - 06/2005)
2. Veiseh, Omid: 14 articles (10/2014 - 06/2005)
3. Fang, Chen: 11 articles (04/2015 - 03/2008)
4. Ellenbogen, Richard G: 10 articles (12/2015 - 07/2007)
5. Zhao, Jinhua: 9 articles (10/2020 - 01/2014)
6. Zhao, Lingzhou: 8 articles (10/2020 - 01/2015)
7. Kievit, Forrest M: 7 articles (12/2015 - 02/2009)
8. Lee, Donghoon: 7 articles (11/2010 - 06/2005)
9. Qiao, Wenli: 6 articles (10/2020 - 01/2014)
10. Wang, Kui: 6 articles (01/2019 - 02/2011)

Related Diseases

1. Glioma (Gliomas)
2. Neoplasms (Cancer)
3. Lung Neoplasms (Lung Cancer)
11/26/2022 - "Chlorotoxin and Lung Cancer: A Targeting Perspective for Drug Delivery."
11/26/2022 - "Given chlorotoxin's promising biological activity, we explore its potential against lung cancer and its utilization for active targeting against this cancer's tumor cells. "
11/26/2022 - "Our analysis indicates that despite the extensive chlorotoxin's research against glioblastoma, lung cancer research with the molecule has been limited, despite some promising early results."
06/01/2006 - "This issue focuses on the following selection of drugs: 131-I-chlorotoxin; Ad5CMV-p53, adalimumab, albumin interferon alfa, alemtuzumab, aliskiren fumarate, aminolevulinic acid methyl ester, anakinra, AR-C126532, atomoxetine hydrochloride; Bevacizumab, bosentan, botulinum toxin type B, brimonidine tartrate/timolol maleate; Calcipotriol/betamethasone dipropionate, cangrelor tetrasodium, cetuximab, ciclesonide, cinacalcet hydrochloride, collagen-PVP, Cypher; Darbepoetin alfa, darusentan, dasatinib, denosumab, desloratadine, dexosome vaccine (lung cancer), dexrazoxane, dextromethorphan/quinidine sulfate, duloxetine hydrochloride; ED-71, eel calcitonin, efalizumab, entecavir, etoricoxib; Falciparum merozoite protein-1/AS02A, fenretinide, fondaparinux sodium; gamma-Hydroxybutyrate sodium, gefitinib, ghrelin (human); hLM609; Icatibant acetate, imatinib mesylate, ipsapirone, irofulven; LBH-589, LE-AON, levocetirizine, LY-450139; Malaria vaccine, mapatumumab, motexafin gadolinium, muraglitazar, mycophenolic acid sodium salt; nab-paclitaxel, nelarabine; O6-Benzylguanine, olmesartan medoxomil, orbofiban acetate; Panitumumab, peginterferon alfa-2a, peginterferon alfa-2b, pemetrexed disodium, peptide YY3-36, pleconaril, prasterone, pregabalin; Ranolazine, rebimastat, recombinant malaria vaccine, rosuvastatin calcium; SQN-400; Taxus, tegaserod maleate, tenofovir disoproxil fumarate, teriparatide, troxacitabine; Valganciclovir hydrochloride, Val-Tyr sardine peptidase, VNP-40101M, vorinostat."
4. Glioblastoma (Glioblastoma Multiforme)
5. Brain Neoplasms (Brain Tumor)

Related Drugs and Biologics

1. Peptides (Polypeptides)
2. Liposomes (Liposome)
3. DNA (Deoxyribonucleic Acid)
4. Proteins (Proteins, Gene)
5. Ligands
6. ferric oxide (iron oxide)
7. Chitosan
8. Small Interfering RNA (siRNA)
9. CY5.5 cyanine dye
10. Immunoglobulin G (IgG)

Related Therapies and Procedures

1. Therapeutics
2. Microelectrodes
3. Drug Therapy (Chemotherapy)
4. Quantum Dots (Quantum Dot)
5. Electrodes (Electrode)