plexin

01/01/2012 - "The findings of our study clearly indicate that Plexin D1 is strongly associated with cellular differentiation in the tissues investigated, and that expression is strongly dependent on the tumor histotype. "
08/25/2009 - "The objective of this study was to examine whether Plexin D1 might be clinically useful as a pan-tumor vessel and pan-tumor cell target in solid tumors. "
02/01/2009 - "In conclusion, this study confirms our previous observations suggesting Plexin B1 as a new prognostic marker in ER positive breast cancers."
10/27/2023 - "Tumor intrinsic- and extrinsic-SEMA3D induced ARF6 signaling through its receptor Plexin D1 in a mutant KRAS-dependent manner. "
04/01/2021 - "A mouse xenograft model was established to evaluate the effect of miR-564 knockdown on tumor growth in vivo, whereas the expression of plexin A4 and Ki67 in NSCLC tissues was detected using immunohistochemistry. "

02/01/2009 - "The goal of the present study was a validation of Plexin B1 expression in a large scale microarray dataset from n=1086 breast cancer patients. "
01/01/2017 - "Loss of plexin B1 expression might play a pivotal role in enhancing the metastatic potential of breast cancer cells."
02/01/2009 - "In the previous work, we demonstrated that the loss of Plexin B1 expression is associated with poor outcome in breast cancer patients. "
02/15/2007 - "Expression data of plexin B1 were obtained from Affymetrix microarray analysis of n = 119 breast cancer specimens. "
02/15/2007 - "However, the biological role of plexin B1 in breast cancer is largely unknown. "

01/01/2017 - "Similarly, reduced plexin B1 expression correlated positively with advanced tumour stage and metastasis. "
01/01/2017 - "In the current study, the role of plexin B1 in breast cancer metastasis was explored. "
02/16/2021 - "Our group has identified Semaphorin-5A (SEMA5A)/Plexin-B3 as an attractive targetable complex for pancreatic cancer (PC) metastasis. "
01/01/2017 - "Furthermore, involvement of plexin B1 in metastasis was explored by generating gene knockdown in MDA-MB-231 and MCF-7 breast cancer cells. "
01/01/2017 - "Role of Plexin B1 in a Breast Cancer Cohort of Pakistani Patients and its Contribution Towards Cancer Metastasis as Indicated by an In Vitro Model."

01/01/2021 - "Plexin A2 downregulation was associated with the promotion of migrative and invasive capacities in B0404 melanoma cells. "
01/01/2015 - "We found that the expression level of Plexin C1 (PlxnC1), a suppressor for melanoma, in a melanoma from an Ednrb(+/-);RET-mouse was drastically decreased compared to that in a melanoma from a RET-mouse. "
10/10/2013 - "In primary melanoma, loss of Plexin C1 may function in early steps of melanoma progression by releasing inhibition of R-Ras activation, and stimulating migration."
10/10/2013 - "Plexin C1 lowered R-Ras activity in melanoma and melanocytes, consistent with inhibitory effects of Plexin C1 on migration of melanocytes and melanoma. "
10/10/2013 - "Plexin C1 significantly inhibited migration and proliferation in melanoma, whereas in melanocytes, loss of Plexin C1 increased migration and proliferation. "

03/01/2007 - "A recent genomewide association study of schizophrenia identified a variant of the gene encoding plexin A2 (PLXNA2) to be most consistently associated across study samples. "
01/01/2011 - "The plexin A2 gene (PLXNA2) has been reported to be associated with schizophrenia. "
05/01/2006 - "Here, we report the identification of a novel schizophrenia candidate gene on chromosome 1q32, plexin A2 (PLXNA2), in a genome-wide association study using 320 patients with schizophrenia of European descent and 325 matched controls. "
11/08/2022 - "Consistently, increased Sema 3A levels have been detected in brain of patients with schizophrenia and many polymorphisms in Sema 3A or in the Sema 3A receptors, Neuropilins (Npn 1 and 2) and Plexin As (Plxn As), have been associated to autism. "
10/30/2015 - "Semaphorin and plexin gene expression is altered in the prefrontal cortex of schizophrenia patients with and without auditory hallucinations."