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leucyl-aspartyl-valine

Also Known As:

Leu-Asp-Val

Networked: 4 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - leucyl-aspartyl-valine: 4

Experts

1.	Feron, Olivier: 1 article (01/2012)
2.	Gérard, Estelle: 1 article (01/2012)
3.	Marchand-Brynaert, Jacqueline: 1 article (01/2012)
4.	Meulle, Aline: 1 article (01/2012)
5.	Alcock, P J: 1 article (08/2000)
6.	Coath, M: 1 article (08/2000)
7.	Dutta, A S: 1 article (08/2000)
8.	Ferguson, R: 1 article (08/2000)
9.	Gellert, P R: 1 article (08/2000)
10.	Gormley, J J: 1 article (08/2000)

Related Diseases

1.	Leukemia 01/01/2012 - "The tripeptide Leu-Asp-Val (LDV) is known to bind α(4)β(1) integrin in leukemia cells. " 05/27/2023 - "Functionalization of the LNPs with a modified Leu-Asp-Val tripeptide, a specific ligand for the very-late antigen 4 resulted in an improved uptake and functional siRNA delivery in patient-derived leukemia cells when compared to their non-targeted counterparts. "
2.	Melanoma (Melanoma, Malignant) 01/01/1992 - "In the present studies, using a series of peptides derived from CS-1, we identify the tripeptide leu-asp-val (LDV), as the minimal peptide capable of supporting stable lymphocyte or melanoma cell adhesion. "
3.	Hypersensitivity (Allergy) 08/01/2000 - "Many of the peptides like cyclo(MePhe-Leu-Asp-Val-D-Arg-D-Arg) (ZD7349) (17), cyclo(MeIle-Leu-Asp-Val-D-Arg-D-Arg-D-Phe) (20), cyclo(MeIle-Leu-Asp-Val-D-Arg-D-Arg-MePhe) (21) and cyclo(MePhe-Leu-Asp-Val-D-Arg-D-Arg-D-Ala-D-Ala) (23) were potent inhibitors of VLA-4-mediated cell adhesion and inhibited ovalbumin-induced delayed type hypersensitivity (DTH) response in mice. "

Related Drugs and Biologics

1.	Integrin alpha4beta1 (VLA-4)
2.	Small Interfering RNA (siRNA)
3.	Ligands
4.	Peptides (Polypeptides)
5.	Integrins
6.	Ovalbumin
7.	ZD7349
8.	alanylalanine (Ala-Ala)