HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

4,7beta-dimethyl-4-azacholestan-3-one

structure given in first source

Also Known As:

MK 386; MK-386

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Heterocyclic Steroids: 4
      - Azasteroids: 4
        4,7beta-dimethyl-4-azacholestan-3-one: 2

Related Diseases

1.	Acne Vulgaris 01/01/1996 - "MK-386, LY191704) may be regarded as candidates for treatment of androgen-dependent skin disorders such as seborrhoea, acne, hirsutism and/or androgenetic alopecia." 01/01/1997 - "Using this model for human acne, we examined the effects of inhibitors of human steroid 5 alpha-reductase isozymes, type I (MK 386) and type II (finasteride), and an androgen receptor blocker (RU58841) on regression of glandular and ductal hyperplasia. "
2.	Hyperplasia 01/01/1997 - "Using this model for human acne, we examined the effects of inhibitors of human steroid 5 alpha-reductase isozymes, type I (MK 386) and type II (finasteride), and an androgen receptor blocker (RU58841) on regression of glandular and ductal hyperplasia. "
3.	Hirsutism 01/01/1996 - "MK-386, LY191704) may be regarded as candidates for treatment of androgen-dependent skin disorders such as seborrhoea, acne, hirsutism and/or androgenetic alopecia."
4.	Alopecia (Baldness) 01/01/1996 - "MK-386, LY191704) may be regarded as candidates for treatment of androgen-dependent skin disorders such as seborrhoea, acne, hirsutism and/or androgenetic alopecia."

Related Drugs and Biologics

1.	Finasteride (Propecia)
2.	3-Oxo-5-alpha-Steroid 4-Dehydrogenase (Testosterone 5 alpha Reductase)
3.	Androgen Receptors (Androgen Receptor)
4.	Isoenzymes
5.	Androgens
6.	RU 58841