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delta catenin

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CTNND1 is a substrate of protein-tyrosine kinase receptors; RefSeq NM_008729 (Ctnnd2, mouse); NM_001331 (CTNND1, human); XM_242062 (Ctnnd1, rat); NM_007615 (Ctnnd1, mouse)

Also Known As:

135-kDa NPRAP protein, mouse; CTNND protein, human; CTNND1 protein, human; CTNND2 protein, human; Catnd2 protein, mouse; Catns protein, rat; Ctnnd protein, mouse; Ctnnd1 protein, mouse; Ctnnd1 protein, rat; Ctnnd2 protein, mouse; NPRAP protein, human; NPRAP protein, mouse; P120CAS protein, human; P120CTN protein, human; cadherin-associated Src substrate p120; cadherin-associated protein p100, Canis familiaris; catenin (cadherin associated protein), delta 1 protein, mouse; catenin (cadherin associated protein), delta 2, mouse; catenin (cadherin-associated protein), delta 1, human; catenin (cadherin-associated protein), delta 2, human; catenin delta 2 protein, human; catenin delta 2 protein, mouse; catenin delta-1; catenin delta-2; catenin p120(ctn) protein; catenin p120ctn protein; catenin src protein, rat; catenin, delta; delta catenin protein, human; delta catenins; delta-catenin; delta-catenin, human; neural plakophilin-related arm-repeat protein, human; neural plakophilin-related arm-repeat protein, mouse; neurojungin; neurojungin protein, mouse; p100 cadherin-associated protein, Canis familiaris; p120(cas); p120(ctn); p120-catenin; p120-catenin protein, mouse; p120Cas protein, mouse; p120Ctn protein, mouse; p120cas; p120cas protein, rat; p120ctn; p120ctn protein, rat

Networked: 182 relevant articles (2 outcomes, 31 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins
- Proteins: 90489
  - Cytoskeletal Proteins: 557
    - Catenins: 248
      - delta catenin: 182

Experts

1.	Liu, Yang: 19 articles (06/2015 - 04/2005)
2.	Wang, En-Hua: 13 articles (06/2015 - 07/2007)
3.	Wang, Enhua: 13 articles (06/2015 - 08/2005)
4.	Miao, Yuan: 9 articles (06/2015 - 04/2008)
5.	Reynolds, Albert B: 9 articles (09/2014 - 12/2002)
6.	Dai, Shun-Dong: 9 articles (03/2014 - 07/2007)
7.	Wang, Yan: 8 articles (12/2012 - 04/2008)
8.	Lu, Qun: 8 articles (10/2010 - 10/2005)
9.	Zhang, Di: 7 articles (06/2015 - 08/2008)
10.	Zhao, Yue: 6 articles (06/2015 - 03/2009)

Related Diseases

1.	Carcinoma (Carcinomatosis) 10/01/1999 - "The aim of this study was to investigate in vivo expression of p120(ctn) in gastric carcinoma and to examine any relationship to pathological characteristics and patient survival. " 09/01/1999 - "In this study, we evaluated immunohistochemically the expression and cellular localization of p120cas in 40 gastric, 43 colorectal and 20 pancreatic carcinomas, and examined the relationship between p120cas expression and pathological features. " 01/01/2013 - "Furthermore, it suggests that loss of p120-catenin expression and cytoplasmic localization of β-catenin fine-tune the carcinoma progression. " 05/02/2008 - "delta-Catenin is upregulated in human carcinomas. " 03/01/2008 - "Our findings suggest that p120(ctn) acts as a prognostic factor in bladder tumours and has a primary role to play in the migratory and invasive behaviour of bladder carcinoma cells."
2.	Ventilator-Induced Lung Injury 01/01/2015 - "Protective role of p120-catenin in maintaining the integrity of adherens and tight junctions in ventilator-induced lung injury." 08/01/2011 - "Our findings demonstrate that p120-catenin plays a critical protective role in cyclic stretch-induced alveolar barrier dysfunction, and, thus, maintenance of p120-catenin expression may be a novel therapeutic strategy for the prevention and treatment of ventilator-induced lung injury." 04/01/2011 - "This study tested the hypothesis that Rho negative regulator p190RhoGAP is essential for OxPAPC-induced lung barrier protection against ventilator-induced lung injury (VILI), and investigated potential mechanism of p190RhoGAP targeting to adherens junctions (AJ) via p120-catenin. "
3.	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/01/2015 - "The aim of this study was to investigate correlations between altered localization of p120ctn and clinical-pathological characteristics in esophageal squamous cell carcinoma (ESCC). " 06/01/2013 - "To date, there have only been two studies examining expression levels of p120ctn in oral squamous cell carcinoma (OSCC). " 04/01/2012 - "Recent studies have shown that phosphorylation of p120-catenin (p120) promotes progression and invasion of oral squamous cell carcinoma (OSCC) cells. " 06/01/2013 - "Is expression of p120ctn in oral squamous cell carcinomas a prognostic factor?" 08/09/2007 - "p120-catenin is required for the collective invasion of squamous cell carcinoma cells via a phosphorylation-independent mechanism."
4.	Neoplasms (Cancer) 01/01/2012 - "Studies have demonstrated that p120-catenin plays important roles in cell-cell adhesion, embryonic development, cell proliferation and polarity, tumor cell migration, and cancer progression. " 10/01/2010 - "For most epithelial cancers, studies have demonstrated a reduction of p120(ctn) expression or alteration of its subcellular distribution. " 04/01/2003 - "This study further represents conclusive evidence for a direct involvement of p120(ctn) in malignant tumor cell proliferation. " 06/01/2015 - "The immunohistochemical expression of α-, β- and p120-catenin was studied in a series of normal feline mammary glands, hyperplastic/dysplastic lesions and benign and malignant mammary tumors. " 01/01/2015 - "The high ratio of membrane expression to overall cellular expression (M/C) of p120ctn was inversely associated with lymph node invasion (P = 0.001), tumor differentiation (P = 0.012) and advanced tumor stage (P = 0.005); however, it was poorly associated with T stage (P = 0.274). "
5.	Lung Neoplasms (Lung Cancer) 06/01/2011 - "In the present study, we show that p120-catenin isoform 3 interacts with Kaiso in lung cancer cells by immunoprecipitation. " 06/01/2015 - "Zbed3 contributes to malignant phenotype of lung cancer via regulating β-catenin and P120-catenin 1." 01/01/2014 - "We have reported that p120-catenin could regulate β-catenin transcription in lung cancer cells, but the specific mechanism is unclear. " 06/01/2013 - "Accordingly, the down-regulation and cytoplasmic mislocalization of p120ctn has been reported in all subtypes of lung cancers and is associated with grave prognosis. " 01/06/2012 - "Mislocalization and/or loss of p120ctn have been reported in all lung cancer subtypes and are related to poor prognosis. "

Related Drugs and Biologics

1.	oxidized- L- alpha- 1- palmitoyl- 2- arachidonoyl- sn- glycero- 3- phosphorylcholine
2.	Small Interfering RNA (siRNA)
3.	Cadherins (E-Cadherin)
4.	beta Catenin
5.	delta catenin
6.	Protein Isoforms (Isoforms)
7.	Phosphotransferases (Kinase)
8.	gamma Catenin (Plakoglobin)
9.	alpha Catenin (alpha E-Catenin)
10.	Carbon Monoxide

Related Therapies and Procedures

1.	Heterologous Transplantation (Xenotransplantation)
2.	Therapeutics
3.	Prostatectomy (Retropubic Prostatectomy)
4.	Lasers (Laser)
5.	Drug Therapy (Chemotherapy)