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steroidogenic acute regulatory protein

a luteinizing hormone-induced mitochondrial protein isolated from murine Leydig tumor cells; also found in normal tissues; amino acid sequence in first source
Also Known As:
STAR protein, human; STARD1 protein, human; Star protein, mouse; Star protein, rat; star protein, zebrafish; steroidogenic acute regulator protein, human; steroidogenic acute regulatory protein, mouse; steroidogenic acute regulatory protein, rat; steroidogenic acute regulatory protein, zebrafish
Networked: 186 relevant articles (1 outcomes, 15 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Manna, Pulak R: 7 articles (06/2022 - 02/2002)
2. Stocco, Douglas M: 5 articles (01/2009 - 11/2002)
3. Miller, Walter L: 4 articles (02/2015 - 12/2006)
4. Achermann, John C: 4 articles (07/2010 - 09/2005)
5. Ahmed, Ahsen U: 3 articles (06/2022 - 01/2019)
6. Pruitt, Kevin: 3 articles (06/2022 - 01/2019)
7. Ning, Guang: 3 articles (01/2021 - 09/2010)
8. Bose, Himangshu S: 3 articles (02/2020 - 07/2003)
9. Flück, Christa E: 3 articles (01/2020 - 09/2005)
10. Li, Xiaobo: 3 articles (11/2017 - 11/2012)

Related Diseases

1. Diabetes Mellitus
2. Neoplasms (Cancer)
3. Dosage-sensitive sex reversal
12/01/2004 - "Regulation of steroidogenesis and steroidogenic acute regulatory protein in R2C cells by DAX-1 (dosage-sensitive sex reversal, adrenal hypoplasia congenita, critical region on the X chromosome, gene-1)."
04/01/2001 - "Screening for mutations in the steroidogenic acute regulatory protein and steroidogenic factor-1 genes, and in CYP11A and dosage-sensitive sex reversal-adrenal hypoplasia gene on the X chromosome, gene-1 (DAX-1), in hyperandrogenic hirsute women."
12/01/2006 - "In this study, we investigated the effect of dexamethasone on the synthesis of steroidogenic acute regulatory protein (StAR) and the expression of DAX-1 (dosage sensitive sex reversal adrenal hypoplasia congenita critical region on the X chromosome, gene 1) and SF-1 (steroidogenic factor-1) in vivo. "
04/01/2015 - "Rats were killed 6 hours after the injection, and the adrenal glands were collected for measurement of steroidogenic acute regulatory protein, steroidogenic factor 1, and dosage-sensitive sex reversal, adrenal hypoplasia critical region, on chromosome X, gene 1 messenger RNAs and protein using real-time quantitative polymerase chain reaction and Western immunoblotting, respectively. "
09/01/2010 - "DAX1 (for dosage-sensitive sex reversal, adrenal hypoplasia congenital critical region on the X chromosome, gene 1; also called NROB1) mutations are responsible for adrenal failure and hypogonadotropic hypogonadism in patients with adrenal hypoplasia congenita (AHC), through a loss of trans-repression of SF-1 (for steroidogenic factor-1)-mediated StAR (for steroidogenic acute regulatory protein) and LHbeta transcriptional activities and a reduction of GnRH expression. "
4. Adrenocortical Carcinoma
5. Endometriosis

Related Drugs and Biologics

1. Proteins (Proteins, Gene)
2. Oxidoreductases (Dehydrogenase)
3. Testosterone (Sustanon)
4. Androgen Receptors (Androgen Receptor)
5. Niacinamide (Nicotinamide)
6. Messenger RNA (mRNA)
7. Steroids
8. Enzymes
9. Steroidogenic Factor 1
10. Transcription Factors (Transcription Factor)

Related Therapies and Procedures

1. Therapeutics