EDNsFv anti-transferrin receptor

human recombinant eosinophil-derived neurotoxin fused to sFv, a single chain antibody; amino acid sequence known

Also Known As:

EDNsFv; EDNsFv anti-transferrin receptors; anti-transferrin receptor, EDNsFv

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Neoplasms (Cancer) 10/28/1994 - "In contrast to rEDN that had no inherent cytotoxicity to human tumor cells, the EDNsFv fusion protein was cytotoxic to human leukemia cells that express the human transferrin receptor with an IC50, 0.2-1 nM. At 1.3 nM EDNsFv, no cytotoxicity was observed on cells that lack the human transferrin receptor. "
2.	Leukemia 10/28/1994 - "In contrast to rEDN that had no inherent cytotoxicity to human tumor cells, the EDNsFv fusion protein was cytotoxic to human leukemia cells that express the human transferrin receptor with an IC50, 0.2-1 nM. At 1.3 nM EDNsFv, no cytotoxicity was observed on cells that lack the human transferrin receptor. "

1.	Transferrin Receptors (Transferrin Receptor)
2.	Proteins (Proteins, Gene)