DD 003

03/01/1996 - "[Colon cancer and vitamin D--in vivo growth inhibition of colon cancer by a fluorinated analogue of 1,25-(OH)2D3, DD-003]."
10/01/1994 - "Since chemosensitivity tested by the subrenal capsule assay correlates well with clinical response, DD-003 may be clinically applicable in procedures such as postsurgical chemotherapy of colon cancer."
10/01/1994 - "Inhibition of HT-29 human colon cancer growth under the renal capsule of severe combined immunodeficient mice by an analogue of 1,25-dihydroxyvitamin D3, DD-003."

10/01/1994 - "When DD-003 was withdrawn after 2 weeks of treatment, tumor growth resumed. "
10/01/1994 - "Administration of DD-003 inhibited growth of HT-29 tumor by 63%. "
10/01/1994 - "Tumors in DD-003 treated mice were smaller with less invasion compared to the control. "
10/01/1994 - "Starting 7 days after implantation of HT-29 tumor, mice were given 3 micrograms/kg body weight of DD-003 or the vehicle i.p. "
10/01/1994 - "DD-003 inhibited growth of HT-29 tumor in a dose-dependent manner over the range of 0.1-10 micrograms/kg body weight, with no increase of serum calcium concentration observed at any dose level. "

10/01/1994 - "Starting 7 days after implantation of HT-29 tumor, mice were given 3 micrograms/kg body weight of DD-003 or the vehicle i.p. "
10/01/1994 - "DD-003 inhibited growth of HT-29 tumor in a dose-dependent manner over the range of 0.1-10 micrograms/kg body weight, with no increase of serum calcium concentration observed at any dose level. "