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tris-sulfotyrosyl dodecapeptide-I
the primary sequence is identical to 1142-1153 sequence of the insulin proreceptor
Also Known As:
3S-peptide-I; TRDIY(S)ETDY(S)Y(S)RK-amide; TRDIYETDYYRKamide
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Peptides: 82426
Oligopeptides: 519
tris-sulfotyrosyl dodecapeptide-I: 1
Related Diseases
1.
Insulin Resistance
01/01/1998 - "
These findings provide evidence that 3S-peptide-I may improve insulin responsiveness in intact cells by inhibiting LAR, an enzyme whose activity has been implicated in the pathogenesis of insulin resistance.
"
2.
Hepatocellular Carcinoma (Hepatoma)
01/01/1998 - "
Because of the potential role of the transmembrane PTPase LAR in the regulation of insulin signaling, we assessed the effect of 3S-peptide-I on recombinant LAR PTPase activity and in McA-RH7777 rat hepatoma cells overexpressing full-length LAR protein (McA4B/LAR).
"
Related Drugs and Biologics
1.
Protein Tyrosine Phosphatases
2.
Proteins (Proteins, Gene)
3.
Insulin (Novolin)
4.
Enzymes