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seryl-lysyl-leucine

Also Known As:

SKL tripeptide; Ser-Lys-Leu

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - seryl-lysyl-leucine: 4

Experts

1.	Gao, Xue: 1 article (01/2019)
2.	Pan, Xiaohong: 1 article (01/2019)
3.	Sun, Hongliu: 1 article (01/2019)
4.	Wang, Qiaoyun: 1 article (01/2019)
5.	Yu, Haiying: 1 article (01/2019)
6.	Yu, Jie: 1 article (01/2019)
7.	Zhang, Mengdi: 1 article (01/2019)
8.	Zhang, Yurong: 1 article (01/2019)
9.	Zhu, Wei: 1 article (01/2019)
10.	Bechter, Karl: 1 article (01/2017)

Related Diseases

1.	Zellweger Syndrome (Zellweger's Syndrome) 02/01/1992 - "Furthermore, these results reveal that the process of peroxisomal transport does not involve irreversible modification of the protein, that artificial hybrid substrates can be transported and used as tools to study peroxisomal transport, and that the defect in Zellweger syndrome is indeed the inability to transport proteins containing the Ser-Lys-Leu targeting signal into the peroxisomal lumen." 08/01/1992 - "Microinjected alcohol oxidase was transported into vesicles in normal fibroblasts and also in cell lines derived from patients with Zellweger syndrome, which are unable to transport proteins containing the ser-lys-leu-COOH peroxisomal targeting signal into peroxisomes (Walton et al., 1992). "
2.	Seizures (Absence Seizure) 01/01/2019 - "The inhibition of TSP-1 expression by siRNA or TGF-β1 activation by Leu-Ser-Lys-Leu (LSKL) treatment prevented KA-induced phosphorylation of Smad2/3, angiogenesis, BBB damage, and acute seizures. "
3.	Neuroinflammatory Diseases 01/01/2017 - "The triplet puzzle theory also suggests the formation of putative D2R-CCR2, D2R-CXCR4, and D2R-IL1R2 heteromers in mild neuroinflammation in view of their demonstrated sets of Leu-Tyr-Ser (LYS), Leu-Pro-Phe (LPF), and/or Ser-Leu-Ala (SLA) triplet homologies. "

Related Drugs and Biologics

1.	Carrier Proteins (Binding Protein)
2.	Proteins (Proteins, Gene)
3.	Small Interfering RNA (siRNA)
4.	Thrombospondin 1
5.	Peroxisomal Targeting Signals
6.	leucyl-alanine
7.	leucyltyrosine
8.	alcohol oxidase