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45S ribosomal RNA

Also Known As:

RNA, ribosomal, 45S; 45S rRNA; ribosomal RNA 45S

Networked: 12 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleic Acids: 11752
  - RNA: 69704
    - Ribosomal RNA: 537
      - 45S ribosomal RNA: 12

Experts

1.	Bottero, Virginie: 2 articles (03/2011 - 04/2009)
2.	Chandran, Bala: 2 articles (03/2011 - 04/2009)
3.	Sadagopan, Sathish: 2 articles (03/2011 - 04/2009)
4.	Agarwal, Shreya: 1 article (12/2019)
5.	Bieberich, Charles: 1 article (12/2019)
6.	De Marzo, Angelo M: 1 article (12/2019)
7.	Guner, Gunes: 1 article (12/2019)
8.	Laiho, Marikki: 1 article (12/2019)
9.	Liu, Hester: 1 article (12/2019)
10.	Low, Jin-Yih: 1 article (12/2019)

Related Diseases

1.	Infections 04/01/2009 - "Collectively, these results strongly suggest that by increasing infected endothelial cell 45S rRNA synthesis, proliferation, migration, and angiogenesis, KSHV-induced angiogenin could be playing a pivotal role in the pathogenesis of KSHV infection, including a contribution to the angioproliferative nature of KS lesions. " 04/01/2009 - "Kaposi's sarcoma-associated herpesvirus upregulates angiogenin during infection of human dermal microvascular endothelial cells, which induces 45S rRNA synthesis, antiapoptosis, cell proliferation, migration, and angiogenesis." 03/01/2011 - "During de novo infection of human dermal microvascular endothelial cells (HMVEC-d), Kaposi's sarcoma-associated herpesvirus (KSHV) induced the multifunctional angiogenin (ANG) protein, which entered the nuclei and nucleoli of infected cells and stimulated 45S rRNA gene transcription, proliferation, and tube formation, which were inhibited by blocking ANG nuclear translocation with the antibiotic neomycin (S. " 07/01/1969 - "(ii) Analysis of nuclear RNA of cells infected at high multiplicities by sucrose density gradient centrifugation showed that the synthesis and methylation of 45S rRNA precursor continued at a reduced but significant rate (ca. 30% of control values) at times after infection when no radioactive uridine was incorporated or could be chased into 28S and 18S rRNA. "
2.	Tetraploidy 01/01/2018 - "To investigate nucleolar dominance associated with tetraploidization, we analyzed the changes regarding the genetic traits and expression of 45S rRNA genes in tetraploidy hybrid lineage including F1 allotetraploids (4n = 148) and F2 autotetraploids (4n = 200) derived from the distant hybridization of Carassius auratus red var. (2n = 100) () ×Megalobrama amblycephala (2n = 48) (). "
3.	Paramyxoviridae Infections (Parainfluenza) 02/01/1974 - "It would appear that the conditions of denaturation used (99% dimethyl sulfoxide at 26 C, and reaction with 1.1 M formaldehyde for 10 min at 60 C) do not equally denature parainfluenza virus RNA and other RNAs, such as cellular rRNA, 45S rRNA precursor, and R17 RNA."
4.	T-Cell Leukemia (Leukemia, T Cell) 01/01/2017 - "In MCM2 deficient mice a different set of preferred breakage sites is identified that includes the tumor suppressor gene Tcf3, which is known to contribute to T-lymphocytic leukemias that arise in these mice, and the 45S rRNA gene repeats."
5.	Colorectal Neoplasms (Colorectal Cancer) 11/02/2017 - "Here we find that enhanced precursor 45s ribosomal RNA (pre-45s rRNA) is one of the core mechanisms in promoting the pathogenesis of colorectal cancer (CRC). "

Related Drugs and Biologics

1.	angiogenin
2.	RNA Probes
3.	Nuclear RNA
4.	Uridine
5.	Toyocamycin
6.	Sucrose (Saccharose)
7.	18S Ribosomal RNA
8.	RNA Polymerase I (Polymerase I, RNA)
9.	RNA (Ribonucleic Acid)
10.	Proteins (Proteins, Gene)