Pyrrhocoris apterus pyrrhocoricin protein

a 20-residue proline-rich peptide carrying an O-glycosylated substitution; from the sap-sucking bug Pyrrhocoris apterus; active against Gram-negative bacteria; amino acid sequence given in first source

Also Known As:

pyrrhocoricin protein, Pyrrhocoris apterus; pyrrhocoricin; pyrrhocoricin, Pyrrhocoris apterus

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Pore Forming Cytotoxic Proteins
      - Antimicrobial Cationic Peptides: 414
        Pyrrhocoris apterus pyrrhocoricin protein: 4
  - Arthropod Proteins: 21
    - Insect Proteins: 16
      - Pyrrhocoris apterus pyrrhocoricin protein: 4
- Peptides: 82426
  - Antimicrobial Peptides: 3727
    - Antimicrobial Cationic Peptides: 414
      - Pyrrhocoris apterus pyrrhocoricin protein: 4
  - Antimicrobial Cationic Peptides: 414
    - Pyrrhocoris apterus pyrrhocoricin protein: 4

Experts

1.	Otvos, L: 3 articles (07/2002 - 04/2000)
2.	Bulet, Philippe: 1 article (12/2002)
3.	Condie, Barry A: 1 article (12/2002)
4.	Cudic, Mare: 1 article (12/2002)
5.	Insug, O: 1 article (12/2002)
6.	Lysenko, Elena S: 1 article (12/2002)
7.	Otvos, Laszlo: 1 article (12/2002)
8.	Weiner, Daniel J: 1 article (12/2002)
9.	Xiang, Zhi Q: 1 article (12/2002)
10.	Bokonyi, K: 1 article (04/2000)

Related Diseases

1.	Infections 12/01/2002 - "influenzae lung infection model, a single dose of a dimeric pyrrhocoricin analog reduced the bacteria in the bronchoalveolar lavage when delivered intranasally. " 07/01/2002 - "Pyrrhocoricin derivatives protect mice from experimental infections in vivo, suggesting the utility of modified analogs in the clinical setting. " 04/01/2000 - "At low doses, pyrrhocoricin protected mice against Escherichia coli infection, but at a higher dose augmented the infection of compromised animals. "
2.	Escherichia coli Infections 10/01/2000 - "Indeed, a pyrrhocoricin analogue shows lack of toxicity in vitro and in vivo and protects mice against experimental Escherichia coli infection. " 04/01/2000 - "At low doses, pyrrhocoricin protected mice against Escherichia coli infection, but at a higher dose augmented the infection of compromised animals. "