FLEP regimen

a chemotherapy protocol consisting of the above compounds; used in the treatment of locally advanced or metastatic carcinoma of the oesophagus; do not confuse with FLEP protocol

Networked: 4 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Therapy Context: Research Results

Therapeutics: 1158551
- Drug Therapy: 293145
  - Combination Drug Therapy: 12066
    - Antineoplastic Combined Chemotherapy Protocols: 35
      - FLEP regimen: 4
  - Antineoplastic Protocols: 55
    - Antineoplastic Combined Chemotherapy Protocols: 35
      - FLEP regimen: 4
- Clinical Protocols
  - Antineoplastic Protocols: 55
    - Antineoplastic Combined Chemotherapy Protocols: 35
      - FLEP regimen: 4
Inorganic Chemicals: 9
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidinones: 71
      - Uracil: 1493
        Fluorouracil: 26711
        FLEP regimen: 4
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Pteridines: 147
      - Pterins: 160
        Folic Acid: 19425
        Tetrahydrofolates: 8
        Formyltetrahydrofolates
        Leucovorin: 5743
        FLEP regimen: 4
Enzymes and Coenzymes: 1
- Coenzymes: 558
  - Tetrahydrofolates: 8
    - Formyltetrahydrofolates
      - Leucovorin: 5743
        FLEP regimen: 4
Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        Tetrahydronaphthalenes: 1
        Podophyllotoxin: 562
        Etoposide: 10706
        FLEP regimen: 4
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - Tetrahydronaphthalenes: 1
      - Podophyllotoxin: 562
        Etoposide: 10706
        FLEP regimen: 4
Carbohydrates: 22023
- Glycosides: 2119
  - Glucosides: 639
    - Etoposide: 10706
      - FLEP regimen: 4

Experts

1.	Fujii, Masashi: 1 article (09/2002)
2.	Kanamori, Noriaki: 1 article (09/2002)
3.	Kasakura, Yuichi: 1 article (09/2002)
4.	Kochi, Mitsugu: 1 article (09/2002)
5.	Mochizuki, Fumiro: 1 article (09/2002)
6.	Takayama, Tadatoshi: 1 article (09/2002)
7.	Wakabayashi, Kazuhiko: 1 article (09/2002)
8.	Yamagata, Motoo: 1 article (09/2002)
9.	Eguchi, T: 1 article (10/2001)
10.	Fujii, M: 1 article (10/2001)

Related Diseases

1.	Stomach Neoplasms (Stomach Cancer) 10/01/2001 - "Based on the encouraging response rate and the improvement in prognosis, we recommend the FLEP regimen for patients with primary gastric cancer. " 11/01/1993 - "The FLEP regimen is an active combination in advanced gastric cancer with moderate toxicity that warrants further testing in a phase III trial." 09/01/2002 - "Based on the encouraging response rate and prognosis, we recommend applying the FLEP regimen to patients with primary advanced gastric cancer." 09/01/2002 - "The FLEP regimen (5-FU, LV, ETP, and CDDP) has been recommended as a combination chemotherapy to control advanced and recurrent gastric cancer. " 10/01/2001 - "The FLEP regimen (5-FU, LV, ETP and CDDP) is a combination chemotherapy administered regionally and systemically for the control of both local and disseminated disease in intra- and extra-abdominal regions in patients with advanced and recurrent gastric cancer. "
2.	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 09/01/1997 - "Combined-modality therapy with FLEP regimen and radiation is a promising treatment with a high response rate and acceptable toxicity for locally advanced non-small cell lung cancer."

Related Therapies and Procedures

1.	Combined Modality Therapy
2.	Combination Drug Therapy (Combination Chemotherapy)