alpha-conotoxin ImI

a nicotinic acetylcholine receptor ligand isolated from the snail Conus imperialis

Also Known As:

Gly-Cys-Cys-Ser-Asp-Pro-Arg-Cys-Ala-Trp-Arg-Cys-NH2; alpha-CTx-ImI; glycyl-cysteinyl-cysteinyl-seryl-asparginyl-prolyl-arginyl-cysteinyl-alanyl-tryptophyl-arginyl-cysteinamide; L-Cysteinamide, glycyl-L-cysteinyl-L-cysteinyl-L-seryl-L-alpha-aspartyl-L-prolyl-L-arginyl-L-cysteinyl-L-alanyl-L-tryptophyl-L-arginyl-, cyclic (2-8),(3-12)-bis(disulfide)

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Seizures (Absence Seizure) 08/01/1995 - "Through a study of cloned nicotinic receptors expressed in Xenopus oocytes, we provide evidence that alpha-conotoxin ImI, a peptide marine snail toxin that induces seizures in rodents, selectively blocks subtypes of nicotinic acetylcholine receptors. "

Related Drugs and Biologics

1.	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)
2.	Peptides (Polypeptides)