C.I. Acid Red 114

source gives many trade names; structure in first source

Also Known As:

8-((3,3'-dimethyl-4'-((4-(((4-methylphenyl)sulfonyl)oxy)phenyl)azo)(1,1'-biphenyl)-4-yl)azo)-7-hydroxy-1,3-naphthalenedisulfonic acid disodium salt; Acid Leather Red BG; Acid Red 114; C.I. Acid Red 114, disodium salt; CI Acid Red 114; Erionyl Red RS

Networked: 3 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Clayton, Natasha P: 1 article (01/2005)
2.	Flagler, Norris D: 1 article (01/2005)
3.	Johnson, Jo Anne: 1 article (01/2005)
4.	Kissling, Grace E: 1 article (01/2005)
5.	Nyska, Abraham: 1 article (01/2005)
6.	Yoshizawa, Katsuhiko: 1 article (01/2005)

Related Diseases

1.	Neoplasms (Cancer) 12/01/1991 - "Conclusions: Under the conditions of these 2-year drinking water studies, there was clear evidence of carcinogenic activity of C.I. Acid Red 114 for male F344/N rats, as indicated by benign and malignant neoplasms of the skin, Zymbal's gland, and liver. " 01/01/1989 - "Neoplasms of preputial gland and skin were obtained from Fischer 344 male rats on lifetime drinking water studies of the benzidine congener 3,3'-dimethoxybenzidine, C.I. Direct Blue 15 or C.I. Acid Red 114, bisazobiphenyl dyes derived from 3,3'-dimethoxybenzidine and 3,3'-dimethylbenzidine. "
2.	Carcinogenesis 12/01/1991 - "Toxicology and carcinogenesis studies were conducted by administering desalted, industrial grade C.I. Acid Red 114 in drinking water to groups of F344/N rats of each sex for 13 days, 13 weeks, 9 or 15 months, or 2 years. " 12/01/1991 - "Toxicology and Carcinogenesis Studies of C.I. Acid Red 114 (CAS No. 6459-94-5) in F344/N Rats (Drinking Water Studies)."
3.	Thrombosis (Thrombus) 01/01/2005 - "Incidences of atrial thrombosis were increased in high-dosed groups involving 13 compounds (incidence rate: 20-100%): 2-butoxyethanol, C.I. Direct Blue 15, bis(2-chloroethoxy)methane, diazoaminobenzene, diethanolamine, 3,3'-dimethoxybenzidine dihydrochloride, hexachloroethane, isobutene, methyleugenol, oxazepam, C.I. Pigment Red 23, C.I. Acid Red 114, and 4,4'-thiobis(6-t-butyl-m-cresol). "
4.	Chromosome Aberrations (Chromosome Abnormalities) 12/01/1991 - "C.I. Acid Red 114 did not induce sister chromatid exchanges or chromosomal aberrations in Chinese hamster ovary cells with or without S9 activation; reductive metabolism was not used in these cytogenetic tests. "

Related Drugs and Biologics

1.	Drinking Water
2.	Dianisidine
3.	direct blue 15
4.	Coloring Agents (Dyes)
5.	benzidine
6.	2-tolidine
7.	Oxazepam (Serax)
8.	1- (2- methoxy- 5- nitrophenylazo)- 2- hydroxy- 3- (3- nitrophenylcarbamoyl)naphthalene (Red 23)
9.	bis(2-chloroethoxy)methane
10.	1,3-diphenyl-1-triazene