calmegin

a testis-specific endoplasmic reticulum-associated protein expressed during mammalian spermatogenesis; 101 kDa

Also Known As:

CLGN protein, human; Clgn protein, mouse; calmegin protein, human; calmegin protein, mouse; calnexin-t

Networked: 9 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Carrier Proteins: 12999
    - Calcium-Binding Proteins: 1333
      - calmegin: 9
  - Molecular Chaperones: 1279
    - calmegin: 9

Experts

1.	Okabe, Masaru: 5 articles (05/2011 - 09/2004)
2.	Ikawa, Masahito: 4 articles (01/2011 - 09/2004)
3.	Yamaguchi, Ryo: 3 articles (07/2009 - 09/2004)
4.	Muro, Yuko: 2 articles (05/2011 - 07/2009)
5.	Inoue, Naokazu: 2 articles (01/2011 - 01/2007)
6.	Isotani, Ayako: 2 articles (07/2009 - 09/2004)
7.	Baba, Ryuta: 1 article (01/2020)
8.	Gomez-Sanchez, Celso E: 1 article (01/2020)
9.	Gomez-Sanchez, Elise P: 1 article (01/2020)
10.	Hattori, Noboru: 1 article (01/2020)

Related Diseases

1.	Male Infertility (Male Sterility) 01/01/2011 - "However, this is not likely, as there are already six different gene-disrupted mouse lines (Calmegin, Adam1a, Adam2, Adam3, Ace and Pgap1), all of which result in male sterility. " 12/19/1997 - "The putative chaperone Calmegin is required for sperm fertility in mouse and the relevance of the gene to certain cases of human male infertility has been suggested. " 09/01/2004 - "Loss of calmegin, a testis-specific putative chaperone protein of the endoplasmic reticulum, leads to male sterility because the sperm show defects in migration into the oviduct and do not bind to the zona pellucida. "
2.	Herpes Zoster 05/01/2011 - "Unexpectedly, sperm from 5 different gene-disrupted mouse lines (calmegin (Clgn), Adam1a, Adam2, Adam3, and Ace) all have defective zona-binding ability and oviduct-migrating ability. " 07/01/2009 - "Sperm from four different gene-disrupted mouse lines (calmegin [Clgn], Adam1a, Adam2, and Ace) are known to have defective zona-binding ability. " 01/01/2007 - "In the first half of this review we describe the interaction of ADAMs with calmegin and try to elucidate the relationship of these proteins to establish the zona binding ability. "
3.	Adrenocortical Adenoma (Disease, Conn's) 01/01/2020 - "The ER chaperone calmegin (CLGN) was the most highly expressed ER-associated gene in APAs relative to nonfunctioning adrenocortical adenomas. "
4.	Infertility (Sterility) 06/05/1997 - "The defective zona pellucida-adhesion phenotype of sperm from calmegin-deficient mice is reminiscent of certain cases of unexplained infertility in human males."
5.	Fibrosarcoma 10/31/2005 - "The cDNA microarray analysis of the human fibrosarcoma cells treated with trichostatin A (TSA) showed an increased level of calmegin mRNA. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Complementary DNA (cDNA)
3.	Messenger RNA (mRNA)
4.	Aldosterone
5.	theasinensin A
6.	trichostatin A (A 300)