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CP 113818

structure in first source

Also Known As:

CP 113,818; CP-113,818; CP-113818; N-(2,4-bis(methylthio)-6-methylpyridin-3-yl)-2-(hexylthio)decanoic acid amide

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - CP 113818: 2

Experts

1.	Antalis, Caryl J: 1 article (08/2010)
2.	Arnold, Tyler: 1 article (08/2010)
3.	Buhman, Kimberly K: 1 article (08/2010)
4.	Lee, Bonggi: 1 article (08/2010)
5.	Rasool, Tamkeen: 1 article (08/2010)
6.	Siddiqui, Rafat A: 1 article (08/2010)
7.	Domnitz, Sarah B: 1 article (10/2004)
8.	Eckman, Christopher B: 1 article (10/2004)
9.	Frosch, Matthew P: 1 article (10/2004)
10.	Hofmeister, Alexander: 1 article (10/2004)

Related Diseases

1.	Amyloid Plaque 10/14/2004 - "Two months of treatment with CP-113,818 reduced the accumulation of amyloid plaques by 88%-99% and membrane/insoluble Abeta levels by 83%-96%, while also decreasing brain cholesteryl-esters by 86%. "
2.	Breast Neoplasms (Breast Cancer) 08/01/2010 - "The functional significance of these findings was demonstrated by the observation that the ACAT inhibitor CP-113,818 reduced proliferation of breast cancer cells, and specifically reduced LDL-induced proliferation of ER(-) cells. "
3.	Alzheimer Disease (Alzheimer's Disease) 10/14/2004 - "The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease."

Related Drugs and Biologics

1.	Cholesterol Esters (Cholesteryl Esters)
2.	Amyloid (Amyloid Fibrils)
3.	oxidized low density lipoprotein