melanocortin 5 receptor

belongs to the melanocortin receptor family; responds mainly to alpha-melanocyte-stimulating hormone (MSH); contains 325 amino acid residues; amino acid sequence given in first source; GenBank X76295

Also Known As:

Networked: 14 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Lee, Darren J: 3 articles (01/2021 - 10/2019)
2.	Muhammad, Fauziyya: 2 articles (01/2021 - 11/2019)
3.	Peters, Kayleigh: 2 articles (01/2021 - 10/2019)
4.	Wang, Dawei: 2 articles (11/2019 - 10/2019)
5.	Taylor, A W: 2 articles (08/2009 - 05/2006)
6.	Choe, Yoona: 1 article (05/2022)
7.	Cluckey, David: 1 article (05/2022)
8.	Manhapra, Ambika: 1 article (05/2022)
9.	Ng, Tat Fong: 1 article (05/2022)
10.	Taylor, Andrew W: 1 article (05/2022)

Related Diseases

1.	Obesity 10/01/2019 - "In this study, we assessed EAU in a high-fat diet (HFD) obesity model and found that the EAU severity is significantly higher in wild-type mice, but not in HFD melanocortin 5 receptor deficient mice. " 11/01/2020 - "The melanocortin-5 receptor (mc5r) plays an important role in exocrine function, lipid metabolism, obesity, and stress response in the vertebrate. " 10/01/2019 - "This report demonstrates that obesity exacerbates autoimmune uveitis and inhibits the promotion of post-EAU regulatory immunity through the melanocortin 5 receptor. " 10/01/2019 - "Exacerbation of autoimmune uveitis by obesity occurs through the melanocortin 5 receptor."
2.	Acne Vulgaris 03/01/2021 - "This study failed to detect any association between acne pathogenesis and perilipin 2 and melanocortin 5 receptor serum levels. " 03/01/2021 - "This study sought to determine whether levels of perilipin 2 and melanocortin 5 receptors have an impact on the development of acne vulgaris. " 03/01/2021 - "In the moderate acne group, perilipin 2 and melanocortin 5 receptor levels were significantly higher than in the mild acne group (p = 0.0014, p = 0.003). " 03/01/2021 - "No significant differences were observed between the acne group and the control group in serum perilipin 2 (p = 0.594) and melanocortin 5 receptor (p = 0.213) levels. " 03/01/2021 - "Evaluation of perilipin 2 and melanocortin 5 receptor serum levels with sebogenesis in acne vulgaris patients."
3.	Uveitis 05/19/2022 - "Melanocortin 5 Receptor Expression and Recovery of Ocular Immune Privilege after Uveitis." 11/01/2019 - "Tissue-specific production of MicroRNA-155 inhibits melanocortin 5 receptor-dependent suppressor macrophages to promote experimental autoimmune uveitis." 10/01/2019 - "This report demonstrates that obesity exacerbates autoimmune uveitis and inhibits the promotion of post-EAU regulatory immunity through the melanocortin 5 receptor. " 10/01/2019 - "Exacerbation of autoimmune uveitis by obesity occurs through the melanocortin 5 receptor." 08/01/2009 - "We clinically scored the uveitis over time in B10.RIII, C57BL/6, and melanocortin 5 receptor knock-out (MC5r((-/-))) mice with experimental autoimmune uveitis (EAU) that were conjunctively injected with a naked DNA plasmid encoding ACTH1-17 at the time of EAU onset and three days later. "
4.	Autoimmune Diseases (Autoimmune Disease) 01/01/2021 - "Combined Deficiency of the Melanocortin 5 Receptor and Adenosine 2A Receptor Unexpectedly Provides Resistance to Autoimmune Disease in a CD8+ T Cell-Dependent Manner." 05/30/2006 - "Alpha-MSH through the melanocortin 5 receptor (MC5r) mediates induction of CD4+ regulatory T cells that suppress in an antigen specific manner autoimmune disease. "
5.	Hyperpigmentation 01/01/2018 - "In order to confirm the contribution of ASIP1 and further examine receptor function in the body coloration of Japanese flounder, expression levels of asip1, mc1r, melanocortin 5 receptor (mc5r), and melanin-concentrating hormone receptor 2 (mchr2) were measured in the normally pigmented area of the left side, the normally non-pigmented area of the right side, and the abnormally pigmented (exhibiting hypermelanosis) area of the right side. "

Related Drugs and Biologics

1.	Perilipin-2
2.	Melanocortins
3.	Leptin Receptors
4.	Melanocortin Receptors (Melanocortin Receptor)
5.	Adrenergic Agents (Adrenergic Drugs)
6.	Puromycin Aminonucleoside
7.	Proteins (Proteins, Gene)
8.	Factor VIII (Coagulation Factor VIII)
9.	Epidermal Growth Factor (EGF)
10.	DNA (Deoxyribonucleic Acid)