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N- (2- (mercaptomethyl)- 3- phenylbutanoyl)- L- alanine
structure given in first source
Also Known As:
RB 105; RB-105
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Amino Acids: 30675
Alanine: 4133
N-(2-(mercaptomethyl)-3-phenylbutanoyl)-L-alanine: 2
Related Diseases
1.
Renovascular Hypertension (Goldblatt Syndrome)
04/26/1994 - "
Infusion of RB 105 as a bolus of 25 mg/kg followed by 25 mg/kg per hr similarly decreased blood pressure and increased natriuresis in three different models of hypertension (renovascular, deoxycorticosterone acetate-salt, and spontaneously hypertensive rats).
"
2.
Hypertension (High Blood Pressure)
01/01/1995 - "
In conclusion, RB 105 is a new dual inhibitor of ACE and NEP able to target both blood pressure and renal sodium handling in different experimental renin-dependent and -independent models of hypertension.
"
01/01/1995 - "
Intravenous RB 105 decreased blood pressure similarly in DOCA-salt, renovascular (1C-2K) and spontaneously hypertensive rats and induced a similar natriuretic response in these three different renin-dependent and -independent models of hypertension.
"
Related Drugs and Biologics
1.
Salts
2.
Desoxycorticosterone Acetate (DOCA)
3.
Sodium
4.
Renin
5.
Desoxycorticosterone (Deoxycorticosterone)
6.
Acetates (Acetic Acid Esters)