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CGS 24592

a neutral endopeptidase (NEP) inhibitor; structure given in first source

Also Known As:

3-(N-(2-((phosphonomethyl)amino)-3-(4-biphenylyl)propionyl)amino)propionic acid; CGS-24592; CGS24592

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Essential Amino Acids: 1152
    - Phenylalanine: 4090
      - CGS 24592: 2
  - Cyclic Amino Acids: 3
    - Aromatic Amino Acids: 467
      - Phenylalanine: 4090
        CGS 24592: 2
Organic Chemicals: 133
- Organophosphorus Compounds: 300
  - Organophosphonates: 424
    - CGS 24592: 2

Experts

1.	Cox, Robert A: 1 article (03/2009)
2.	Deyo, Donald J: 1 article (03/2009)
3.	Hawkins, Hal K: 1 article (03/2009)
4.	Herndon, David N: 1 article (03/2009)
5.	Jacob, Sam: 1 article (03/2009)
6.	Traber, Daniel L: 1 article (03/2009)

Related Diseases

1.	Lung Injury 03/01/2009 - "In conclusion the current study indicates that specific NEP inhibitor CGS 24592 exacerbates the SB-induced lung injury and inflammation in mice."
2.	Inflammation (Inflammations) 03/01/2009 - "In conclusion the current study indicates that specific NEP inhibitor CGS 24592 exacerbates the SB-induced lung injury and inflammation in mice."
3.	Hypertension (High Blood Pressure) 03/20/1998 - "Two simple and sensitive reversed-phase high-performance liquid chromatography (HPLC) methods were developed and validated for the quantitative determination of a novel hypertension drug CGS 25462 and its major metabolites CGS 24592 and CGS 25659 in human plasma. " 03/20/1998 - "Quantitative analytical methods for the determination of a new hypertension drug, CGS 25462, and its metabolites (CGS 25659 and CGS 24592) in human plasma by high-performance liquid chromatography."

Related Drugs and Biologics

1.	CGS 25659
2.	CGS 25462