pfalhesin

a host-encoded adhesin that forms an adhesin/receptor pair with CD36 that is responsible for the pH-dependent portion of cytoadherence/sequestration; amino sequence given in first source

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Amelanotic Melanoma (Amelanotic Melanomas) 03/01/1994 - "Immobilized pfalhesin was used as an affinity matrix to purify CD36 from extracts of C32 amelanotic melanoma cells, which have ICAM-1 as well as CD36 receptors, and bind both parasite cell lines. " 12/01/1995 - "The pfalhesin-coated microspheres specifically bound to C32 amelanotic melanoma cells, whereas microspheres coupled with a scrambled version of residues 546-553 had little binding capacity for melanoma cells. "
2.	Melanoma (Melanoma, Malignant) 12/01/1995 - "The pfalhesin-coated microspheres specifically bound to C32 amelanotic melanoma cells, whereas microspheres coupled with a scrambled version of residues 546-553 had little binding capacity for melanoma cells. "
3.	Malaria 12/01/1995 - "Plasmodium falciparum: the adherence of erythrocytes infected with human malaria can be mimicked using pfalhesin-coated microspheres."
4.	Acute Disease 04/01/1998 - "falciparum erythrocyte membrane protein 1 and "Pfalhesin" (band #3) peptides, indicating that such IgG antibodies are stimulated by acute disease but are lost rapidly after the disease episode. "

Related Drugs and Biologics

1.	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)
2.	Proteins (Proteins, Gene)
3.	Peptides (Polypeptides)
4.	Immunoglobulin G (IgG)
5.	Antibodies

Related Therapies and Procedures

1.	Microspheres (Microsphere)