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glycerol dialkyl nonitol tetraethyl ether

lipid from membrane of Solfolobus solfataricus; structure in first source

Also Known As:

GDNT

Networked: 2 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Lipids: 114793
- Glycerides: 109
  - Diglycerides: 1037
    - glycerol dialkyl nonitol tetraethyl ether: 2

Experts

1.	Chen, Chao: 1 article (01/2013)
2.	Wang, Yongting: 1 article (01/2013)
3.	Yang, Guo-Yuan: 1 article (01/2013)
4.	Jedinak, Andrej: 1 article (11/2011)
5.	Jiang, Jiahua: 1 article (11/2011)
6.	Sliva, Daniel: 1 article (11/2011)

Related Diseases

1.	Stroke (Strokes) 01/01/2013 - "In recent years, studies used stem cells that over-express different neurotrophic factors, such as BDNF, GDNT, or NT3, and found that the delivery of these genetically-modified stem cells to animal models of ischemic stroke is safe and effective, thus suggesting that stem cell-based gene therapy may be a promising treatment for stroke. "
2.	Ischemic Stroke 01/01/2013 - "In recent years, studies used stem cells that over-express different neurotrophic factors, such as BDNF, GDNT, or NT3, and found that the delivery of these genetically-modified stem cells to animal models of ischemic stroke is safe and effective, thus suggesting that stem cell-based gene therapy may be a promising treatment for stroke. "
3.	Neoplasms (Cancer) 11/18/2011 - "In conclusion, mushroom GDNT is a natural agent that has potential as a therapy for invasive breast cancers."
4.	Breast Neoplasms (Breast Cancer) 11/18/2011 - "GDNT suppressed expression of the cell cycle regulatory protein CDC20, which is over-expressed in precancerous and breast cancer cells compared to normal mammary epithelial cells. " 11/18/2011 - "Here we show that ganodermanontriol (GDNT), a Ganoderma alcohol, specifically suppressed proliferation (anchorage-dependent growth) and colony formation (anchorage-independent growth) of highly invasive human breast cancer cells MDA-MB-231. " 11/18/2011 - "Ganodermanontriol (GDNT) exerts its effect on growth and invasiveness of breast cancer cells through the down-regulation of CDC20 and uPA."

Related Drugs and Biologics

1.	Brain-Derived Neurotrophic Factor (BDNF)
2.	Nerve Growth Factors (Neurotrophins)
3.	Proteins (Proteins, Gene)
4.	ganodermanontriol

Related Therapies and Procedures

1.	Therapeutics