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4- aminophenylethyl- 1,4,7,10- tetraazacyclodecane- N,N',N'',N'''- tetraacetic acid
bifunctional chelating agent for radioimmunotherapy studies; structure in first source
Also Known As:
PA-DOTA
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amines: 4871
Aniline Compounds: 46
4-aminophenylethyl-1,4,7,10-tetraazacyclodecane-N,N',N'',N'''-tetraacetic acid: 1
Heterocyclic Compounds: 198
4-aminophenylethyl-1,4,7,10-tetraazacyclodecane-N,N',N'',N'''-tetraacetic acid: 1
Experts
1.
Buchsbaum, Donald J
: 1 article (04/2003)
2.
Roberson, Peter L
: 1 article (04/2003)
3.
Rogers, Buck E
: 1 article (04/2003)
4.
Yokoyama, Shigeru
: 1 article (04/2003)
Related Diseases
1.
Neoplasms (Cancer)
04/01/2003 - "
Uptake and dose distributions in peritoneal LS174T colon tumor xenografts were compared for a humanized construct of the CC49 (HuCC49) high-affinity anti-TAG-72 monoclonal antibody and a construct with the CH2 region deleted (HuCC49DeltaCH2), both labeled with (177)Lu using a PA-DOTA bifunctional chelating agent and injected in the peritoneum.
"
Related Drugs and Biologics
1.
Chelating Agents
2.
Monoclonal Antibodies