molybdopterin synthase

catalyzes the conversion of precursor Z to molybdopterin by addition of dithiolene sulfur groups; RefSeq NM_183418 (human); Escherichia coli molybdopterin synthase is a dimer of dimers containing the MoaD and MoaE proteins

Also Known As:

MOCS2 protein, human; MPT synthase; MoaD protein, E coli; MoaE protein, E coli; molybdenum cofactor synthesis 2 protein, human; molybdopterin converting factor; molybdopterin converting factor, subunit 2 protein, E coli; precursor Z converting factor

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Sulfur Group Transferases
      - Sulfurtransferases: 21
        molybdopterin synthase: 5

Experts

1.	Rajagopalan, K V: 3 articles (01/2008 - 11/2001)
2.	Kana, Bavesh D: 1 article (02/2015)
3.	Machowski, Edith Erika: 1 article (02/2015)
4.	Mizrahi, Valerie: 1 article (02/2015)
5.	Narrandes, Nicole C: 1 article (02/2015)
6.	Daniels, Juma N: 1 article (01/2008)
7.	Schindelin, Hermann: 1 article (01/2008)
8.	Wuebbens, Margot M: 1 article (01/2008)
9.	Araujo, Jose Angel Santamaria: 1 article (07/2003)
10.	Freuer, Andrea: 1 article (07/2003)

Related Diseases

1.	Molybdenum cofactor deficiency 07/11/2003 - "Mechanistic studies of human molybdopterin synthase reaction and characterization of mutants identified in group B patients of molybdenum cofactor deficiency." 11/22/2001 - "Molybdopterin synthase mutations in a mild case of molybdenum cofactor deficiency." 01/15/2008 - "Crystal structure of a molybdopterin synthase-precursor Z complex: insight into its sulfur transfer mechanism and its role in molybdenum cofactor deficiency."
2.	Tuberculosis (Tuberculoses) 02/06/2015 - "tuberculosis together encode a functional MPT synthase. " 02/06/2015 - "tuberculosis genome also contains a moaX gene which encodes an MPT-synthase in which the MoaD and MoaE domains are located on a single polypeptide. "
3.	Complementation Group B Molybdenum Cofactor Deficiency 03/01/1999 - "Human molybdopterin synthase gene: genomic structure and mutations in molybdenum cofactor deficiency type B."

Related Drugs and Biologics

1.	Sulfur
2.	Peptides (Polypeptides)