FLEP protocol

chemotherapy protocol consisting of above compounds; used in treatment of gastric cancer; do not confuse with FLEP regimen

Also Known As:

FaFEC chemotherapy schedule; PELF protocol

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Therapy Context: Research Results

Therapeutics: 1158551
- Drug Therapy: 293145
  - Combination Drug Therapy: 12066
    - Antineoplastic Combined Chemotherapy Protocols: 35
      - FLEP protocol: 1
  - Antineoplastic Protocols: 55
    - Antineoplastic Combined Chemotherapy Protocols: 35
      - FLEP protocol: 1
- Clinical Protocols
  - Antineoplastic Protocols: 55
    - Antineoplastic Combined Chemotherapy Protocols: 35
      - FLEP protocol: 1
Inorganic Chemicals: 9
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidinones: 71
      - Uracil: 1493
        Fluorouracil: 26711
        FLEP protocol: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Pteridines: 147
      - Pterins: 160
        Folic Acid: 19425
        Tetrahydrofolates: 8
        Formyltetrahydrofolates
        Leucovorin: 5743
        FLEP protocol: 1
Enzymes and Coenzymes: 1
- Coenzymes: 558
  - Tetrahydrofolates: 8
    - Formyltetrahydrofolates
      - Leucovorin: 5743
        FLEP protocol: 1
Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthacenes
        Anthracyclines: 9423
        Daunorubicin: 2641
        Doxorubicin: 35390
        Epirubicin: 3820
        FLEP protocol: 1
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthacenes
    - Anthracyclines: 9423
      - Daunorubicin: 2641
        Doxorubicin: 35390
        Epirubicin: 3820
        FLEP protocol: 1
Carbohydrates: 22023
- Glycosides: 2119
  - Aminoglycosides: 5131
    - Anthracyclines: 9423
      - Daunorubicin: 2641
        Doxorubicin: 35390
        Epirubicin: 3820
        FLEP protocol: 1

Experts

1.	Goos, Matthias: 1 article (01/2014)
2.	Illerhaus, Gerald: 1 article (01/2014)
3.	Makowiec, Frank: 1 article (01/2014)
4.	Ruf, Catharina: 1 article (01/2014)
5.	Ruf, Guenther: 1 article (01/2014)
6.	Thomusch, Oliver: 1 article (01/2014)

Related Diseases

Carcinoma (Carcinomatosis)

01/24/2014 - "In patients with advanced gastric carcinoma, neoadjuvant CTx with the PELF- protocol significantly reduces the recurrence rate, especially locoregionally, compared to surgery alone. "
01/24/2014 - "In a retrospective study we analyzed the impact of neoadjuvant chemotherapy (CTx) with the PELF - protocol (Cisplatin, Epirubicin, Leukovorin, 5-Fluoruracil) on mortality, recurrence and prognosis of patients with advanced gastric carcinoma, UICC stages Ib-III. 64 patients were included. "

Related Drugs and Biologics

1.	Epirubicin (Ellence)
2.	Fluorouracil (Carac)
3.	Leucovorin (Folinic Acid)
4.	Cisplatin (Platino)

Related Therapies and Procedures

1.	Neoadjuvant Therapy