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hydroxysafflor yellow A

from Carthamus tinctorius; structure given in first source

Also Known As:

hydroxy safflower yellow pigment A

Networked: 171 relevant articles (12 outcomes, 30 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Ketones: 2618
  - Propiophenones: 1
    - Chalcones: 412
      - Chalcone: 781
        hydroxysafflor yellow A: 171
- Quinones: 434
  - hydroxysafflor yellow A: 171
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Chalcones: 412
        Chalcone: 781
        hydroxysafflor yellow A: 171

Experts

1.	Jin, Ming: 10 articles (10/2019 - 07/2010)
2.	Yu, Li: 6 articles (06/2022 - 07/2017)
3.	Wang, Min: 6 articles (08/2021 - 01/2020)
4.	Bai, Xianyong: 6 articles (04/2021 - 11/2013)
5.	Wen, Aidong: 6 articles (12/2019 - 09/2014)
6.	Liu, Li: 5 articles (07/2022 - 01/2017)
7.	Zhang, Qiong: 5 articles (08/2021 - 01/2020)
8.	Wang, Yu: 5 articles (10/2019 - 01/2014)
9.	Wang, Chaoyun: 5 articles (03/2016 - 11/2013)
10.	He, Yu: 4 articles (06/2022 - 04/2016)

Related Diseases

1.	Reperfusion Injury 12/01/2022 - "Protective effect of hydroxysafflor yellow A on renal ischemia‑-reperfusion injury by targeting the Akt‑Nrf2 axis in mice." 02/19/2020 - "Hydroxysafflor yellow A (HSYA) is an effective therapeutic agent that alleviates myocardial ischaemia/reperfusion injury (MIRI), but the exact mechanisms remain elusive. " 08/13/2010 - "Hydroxysafflor Yellow A protects spinal cords from ischemia/reperfusion injury in rabbits." 07/31/2023 - "Hydroxysafflor yellow A (HSYA), the main active ingredient in the Chinese herbal medicine safflower, exerts significant protective effects against myocardial ischemia/reperfusion injury (MI/RI). " 01/01/2022 - "Protective potential of hydroxysafflor yellow A in cerebral ischemia and reperfusion injury: An overview of evidence from experimental studies."
2.	Brain Ischemia (Cerebral Ischemia) 10/01/2004 - "To study the effects of hydroxysafflor yellow A (HSYA) on the mitochondrial function of cortex mitochondrial during cerebral ischemia in rats. " 05/01/2021 - "Hydroxysafflor yellow A (HSYA) has displayed an impressively essential role in protection of cerebral ischemia/reperfusion (I/R). " 11/01/2020 - "Hydroxysafflor Yellow A Confers Neuroprotection from Focal Cerebral Ischemia by Modulating the Crosstalk Between JAK2/STAT3 and SOCS3 Signaling Pathways." 01/05/2018 - "The purpose of the present work was designed to explore protective cerebrovascular effects of hydroxysafflor yellow A (HSYA), and provide preclinical efficacy and mechanism data for its possible application in patients with cerebral ischemia. " 01/01/2018 - "Hydroxysafflor Yellow A (HSYA) Improves Learning and Memory in Cerebral Ischemia Reperfusion-Injured Rats via Recovering Synaptic Plasticity in the Hippocampus."
3.	Myocardial Ischemia (Ischemic Heart Diseases) 10/12/2016 - "Hydroxysafflor yellow A alleviates myocardial ischemia/reperfusion in hyperlipidemic animals through the suppression of TLR4 signaling." 07/31/2023 - "Hydroxysafflor yellow A (HSYA), the main active ingredient in the Chinese herbal medicine safflower, exerts significant protective effects against myocardial ischemia/reperfusion injury (MI/RI). " 07/31/2023 - "Hydroxysafflor Yellow A Alleviates Acute Myocardial Ischemia/Reperfusion Injury in Mice by Inhibiting Ferroptosis via the Activation of the HIF-1α/SLC7A11/GPX4 Signaling Pathway." 08/01/2019 - "Hydroxysafflor Yellow A mitigated myocardial ischemia/reperfusion injury by inhibiting the activation of the JAK2/STAT1 pathway." 01/01/2021 - "Hydroxysafflor Yellow A Ameliorates Myocardial Ischemia/Reperfusion Injury by Suppressing Calcium Overload and Apoptosis."
4.	Fibrosis (Cirrhosis) 01/01/2016 - "Hydroxysafflor Yellow A Ameliorates Renal Fibrosis by Suppressing TGF-β1-Induced Epithelial-to-Mesenchymal Transition." 01/01/2016 - "The aim of this study was to investigate whether Hydroxysafflor yellow A (HSYA) can preserve renal function by inhibiting the progression of renal fibrosis and the potential mechanisms. " 01/01/2014 - "Our previous studies found that hydroxysafflor yellow A (HSYA), an active ingredient in Carthamus tinctorius L., has anti-inflammatory and anti-fibrosis properties. " 01/01/2012 - "In the present study, we investigated the effect of hydroxysafflor yellow A (HSYA) on hepatic fibrosis and further investigated potential mechanisms in vivo. " 01/01/2014 - "Hydroxysafflor yellow A (HSYA), a major constituent in the hydrophilic fraction of the safflower plant, can retard the progress of hepatic fibrosis. "
5.	Acute Lung Injury 07/01/2010 - "This study is to investigate the pharmacological effect and mechanism of action of hydroxysafflor yellow A (HSYA) on acute lung injury (ALI). " 12/20/2022 - "To investigate the protective effect of hydroxysafflor yellow A (HSYA) against heat stroke (HS)-induced acute lung injury and its possible mechanism. " 12/20/2022 - "[Hydroxysafflor yellow A attenuates heat stroke-induced acute lung injury in mice by inhibiting necroptosis]." 12/01/2014 - "Hydroxysafflor yellow A ameliorates lipopolysaccharide-induced acute lung injury in mice via modulating toll-like receptor 4 signaling pathways." 11/01/2013 - "Hydroxysafflor yellow A suppresses oleic acid-induced acute lung injury via protein kinase A."

Related Drugs and Biologics

1.	3,4-dihydroxyphenyllactic acid
2.	Lipopolysaccharides
3.	7,3'-dihydroxy-4'-methoxyisoflavone
4.	salvianolic acid A
5.	salvianolic acid B
6.	Toll-Like Receptor 4
7.	Toll-Like Receptors (Toll-Like Receptor)
8.	Levodopa (L Dopa)
9.	Calcium
10.	safflower yellow

Related Therapies and Procedures

1.	Therapeutics
2.	Intravenous Injections
3.	Ligation
4.	Chinese Traditional Medicine (Traditional Chinese Medicine)
5.	Intravenous Administration