oxadin

a 2,3-dihydro-6H-1,3,4-oxadiazine product; inhibits a variety of RNA & DNA, as well as retroviruses, in vivo & in vitro; see also record for oxadiarrhot

Also Known As:

2-(4-uracilmethylene)-5-(4-bromophenyl)-6-hydroxy-2,3-dihydro-(6H)-1,3,4-oxadiazine; compound C 6; compound C-6

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Oxazines: 9
    - oxadin: 2

Experts

1.	Gligorich, Keith M: 1 article (01/2013)
2.	Looper, Ryan E: 1 article (01/2013)
3.	Matsen, Cindy B: 1 article (01/2013)
4.	Shelton, Dawne N: 1 article (01/2013)
5.	Sigman, Matthew S: 1 article (01/2013)
6.	Vaden, Rachel M: 1 article (01/2013)
7.	Wang, Guoying: 1 article (01/2013)
8.	Welm, Bryan E: 1 article (01/2013)
9.	Kussovski, V: 1 article (05/2002)
10.	Michailov, Y: 1 article (05/2002)

Related Diseases

1.	Yersinia Infections 05/01/2002 - "A significant immunostimulating effect of Oxadin was found in both experimental groups but was better expressed when administered before Yersinia infection. " 05/01/2002 - "Protective effect of Oxadin on experimental Yersinia enterocolitica infection in rats."
2.	Neoplasms (Cancer) 01/01/2013 - "One compound, C-6, was further characterized for its effect on cell cycle and cell death in cancer cells. " 01/01/2013 - "Compound C-6 was found to inhibit proliferation and induce cell death in tumor cells via a caspase-independent mechanism. "
3.	Infections 05/01/2002 - "After mimicking natural Yersinia enterocolitica systemic infection the number and functional activity of blood leucocytes and peritoneal macrophages were compared between groups of animals treated with Oxadin before and after infection. " 05/01/2002 - "The effect of Oxadin (a new Bulgarian antimicrobial chemotherapeutic agent) on some parameters of non-specific immune response was investigated in a rat model of infection. "

Related Drugs and Biologics

1.	Caspases