Aquavene

09/01/2021 - "As Aquavene materials themselves are commonly considered the cause of hypersensitivity reactions which removed expanding intravenous catheters from the market, this review found several possible substitutes for this material for use in any redesign. "
02/01/1997 - "Recent reports of hypersensitivity-like reactions in some patients catheterized with Landmark catheters have prompted the manufacturer to reexamine biocompatibility data and clinical data to assess whether Aquavene was the source of the patient responses. "
01/01/1997 - "Hypersensitivity-like reactions related to insertion of aquavene-based midline and PICC catheters."
02/01/1997 - "A review of the postmarket surveillance data on Aquavene-based catheters revealed that the reported events were not consistent with a hypersensitivity (immunogenic) response to the biomaterial. "
02/09/1996 - "Since 1990 (1), the Food and Drug Administration (FDA) has received reports of acute hypersensitivity-like reactions temporally associated with insertion of midline catheters made from Aquavene (Landmark, Menlo Care, Menlo Park, California), an elastomeric hydrogel material that becomes hydrated and expands after catheter insertion (FDA, unpublished data, 1995; 1). "

03/15/1998 - "Weight loss within Aquavene on the order of 9% (w/w) over the 24-week flow period indicates that extraction of the noncrosslinked poly(ethylene oxide) hydrogel may be responsible for the prevention of encrustation blockage of this biomaterial. "

02/01/1997 - "Once inside the vein, the Aquavene material becomes hydrated and the catheter swells resulting in minimal trauma to the vein. "