fenspiride (Pneumorel)

01/01/2008 - "Fenspiride addition to COPD treatment improves efficacy of the standard treatment and is recommended for treatment of COPD of stage I and II in combination with broncholytic drugs."
09/01/2002 - "Two french clinical trials have studied the efficacy of fenspiride in patients with acute excerbation or stable COPD and have demonstrated an improvement in the group treated with fenspiride compared with the placebo group."
01/01/2008 - "A comparative randomized trial of fenspiride used for 6 months in combination with broncholytic drugs enrolled 68 COPD patients. "
01/01/2008 - "To study effects of long-term administration of fenspiride in combination with broncholytic drugs on dynamics of clinical symptoms, external respiration function and quality of life in patients with chronic obstructive pulmonary disease (COPD). "
01/01/2007 - "The purpose of the study was to assess the effectiveness and safety of long-term application of fenspiride, an anti-inflammatory drug, in patients with chronic obstructive pulmonary disease (COPD) under outpatient conditions. "

07/01/2005 - "In performed observations in patients with acute bronchitis the high clinical efficacy of fenspiride therapy. "
01/01/2005 - "Efficacy of supplemental anti-inflammatory therapy with fenspiride in chronic obstructive and nonobstructive bronchitis."
07/01/2005 - "Total evaluation of fenspiride efficacy in examined patients with acute bronchitis showed complete relief of symptoms after 7 days of therapy in 24% and after 14 days in 87% of patients. "
07/01/2005 - "Mean duration of acute bronchitis before fenspiride therapy was 2.3+/-1.3 days. "
07/01/2005 - "The efficacy and tolerance of fenspiride therapy have been performed in patients with acute bronchitis. "

08/01/2005 - "[The effect of fenspiride on the number of exacerbations and the time of first exacerbation in patients with chronic bronchitis]."
01/01/1988 - "Efficacy of fenspiride in alleviating SO2 induced chronic bronchitis in rats and allergic rhinitis in guinea pigs."
09/01/2002 - "[Bronchial inflammation during chronic bronchitis, importance of fenspiride]."
01/01/2005 - "The objective of this randomised, nonblind study was to assess the efficacy of fenspiride as complementary anti-inflammatory therapy in combination with ipratropium bromide in patients with chronic bronchitis (CB). "

08/01/2005 - "Quality and quantity of sputum and cough significantly improved in the fenspiride group (comparing to the placebo group p= 0.027 and p = 0.049 adequately for sputum and cough). "
10/01/1995 - "Fenspiride has also been reported to produce a subjective improvement in cough in patients. "
10/01/1995 - "Whether a pathway common to both cough and bronchoconstriction is the site of action of fenspiride remains to be established. "
01/01/2006 - "Fenspiride therapy significantly reduced the indices of sputum parameters (8-fold decrease), incidence of dry rales (6-fold decrease), dyspnoea (4-fold decrease) and cough (2.5-fold decrease). "
10/01/1995 - "Aerosolized capsaicin (30 microM) induced cough was also reduced by 3 and 10 mg.mL-1 aerosolized fenspiride, but no significant effect was found with 1 mg.mL-1. "

06/01/2005 - "Our study show that combined treatment with fenspiride and antibiotic in the treatment of acute otitis media in children causes quicker reduction of symptoms as well as improvement in audiological parameters (tone and impedance)."
01/01/2015 - "The objective of the present study was to estimate the clinical effectiveness of fenspiride used to correct the obstruction of the Eustachian tube in 80 patients presenting with acute tubootitis and exudative otitis media. "
06/01/2005 - "The aim of the study was to observe effectiveness of combined treatment with antibiotic and fenspiride in children with acute otitis media. "
01/01/2015 - "It is concluded that the introduction of fenspiride into combined therapy of acute tubootitis and exudative otitis media promotes the normalization of the ventilation and drainage functions and relieves the severity of subjective clinical symptoms. "
01/01/2013 - "The objective of the present work was to estimate the effectiveness and safety of combined anti-inflammatory therapy of exudative otitis media with the use of fenspiride (erespal). "